Occurrence Of Skeletal-Related Events (SRE) In Patients With Solid Tumors (ST) And Multiple Myeloma (MM) In Germany: Early Versus Late Initiation of Sre Preventative Agents (SPA)

OBJECTIVES: in patients with ST and bone metastases (BM) or with MM, SREs are serious and common complications impacting life expectancy and quality of life. This exploratory and descriptive analysis estimated the time from diagnosis to occurrence of first and subsequent SRE in patients with early v...

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Bibliographic Details
Published in:Value in health 2017-10, Vol.20 (9), p.A417
Main Authors: Intorcia, M, Hohmann, D, Giannopoulou, C, Ansorge, S
Format: Article
Language:English
Subjects:
Bisphosphonates
Bones
Confidence intervals
Diagnosis
Inpatient care
Kidney diseases
Life expectancy
Life span
Medical diagnosis
Metastases
Metastasis
Monoclonal antibodies
Multiple myeloma
Myeloma
Newly diagnosed
Osteoporosis
Patients
Quality of life
Solid tumors
Targeted cancer therapy
Tumors
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Summary:OBJECTIVES: in patients with ST and bone metastases (BM) or with MM, SREs are serious and common complications impacting life expectancy and quality of life. This exploratory and descriptive analysis estimated the time from diagnosis to occurrence of first and subsequent SRE in patients with early versus late treatment initiation with SPA. METHODS: This was a retrospective analysis of a German sick-fund claims database (covering -4 million patients) which includes data from 2007 to 2015. Patients with a diagnosis of ST coded with at least two outpatient or one inpatient diagnoses and newly diagnosed with BM after 07/2011 and patients newly diagnosed with MM after 07/2011, aged >18 years were included. All patients received either denosumab or bisphosphonates within 9 months from study inclusion. The study described the time from BM or MM diagnosis to occurrence of first and subsequent SRE in patients with early (
ISSN:1098-3015
1524-4733
DOI:10.1016/j.jval.2017.08.113