Studies of PLGA Microspheres

Poly(DL-lactide-co-glycolide) (PLGA) has been used to prepare microspheres that possess tremendous potential to release a drug in a controlled manner.5,6 Previously, several attempts have been made to gain more understanding about the effect of changing different process parameters on the characteri...

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Bibliographic Details
Published in:Pharmaceutical technology Europe 2004-05, Vol.16 (5), p.23
Main Authors: Dubey, Rajesh R, Parikh, Rajesh H
Format: Article
Language:English
Subjects:
Drug delivery systems
Morphology
Parikh, Rajesh H
Particle size
Pharmaceuticals
Polymers
Polyvinyl alcohol
X-rays
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Summary:Poly(DL-lactide-co-glycolide) (PLGA) has been used to prepare microspheres that possess tremendous potential to release a drug in a controlled manner.5,6 Previously, several attempts have been made to gain more understanding about the effect of changing different process parameters on the characteristics of PLGA microspheres.7,9 In this article, the authors have determined the effect of two process parameters (drug and polymer concentration) on selected pharmaceutical characteristics of PLGA microspheres.
ISSN:1753-7967