Production of a Novel Material Based on a Collagen–Chitosan Composite and Ibuprofen in a Supercritical Medium

A novel material for biomedical applications was obtained from a collagen–chitosan composite and ibuprofen by a fluid process using supercritical carbon dioxide. The material was characterized by IR and X-ray photoelectron spectroscopy. The applicability of XPS analysis of biomaterials for quantific...

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Bibliographic Details
Published in:Doklady. Physical chemistry (1991) 2018-09, Vol.482 (1), p.130-133
Main Authors: Said-Galiev, E. E., Rubina, M. S., Naumkin, A. V., Ikonnikov, N. S., Vasil’kov, A. Yu
Format: Article
Language:English
Subjects:
Biomedical materials
Carbon dioxide
Chemical compounds
Chemistry
Chemistry and Materials Science
Chitosan
Collagen
Ibuprofen
Infrared spectroscopy
Nonsteroidal anti-inflammatory drugs
Pharmacology
Physical Chemistry
X ray photoelectron spectroscopy
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Summary:A novel material for biomedical applications was obtained from a collagen–chitosan composite and ibuprofen by a fluid process using supercritical carbon dioxide. The material was characterized by IR and X-ray photoelectron spectroscopy. The applicability of XPS analysis of biomaterials for quantification of loaded therapeutic agents is demonstrated.
ISSN:0012-5016
1608-3121
DOI:10.1134/S0012501618090038