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Biocompatibility of the Ti81Nb13Ta3Zr3 Alloy

Titanium-based alloy with low-toxic metals such as niobium, tantalum and zirconium (TiNbTaZr) was manufactured. The primary weight percentages of elements used for fusion were: titanium, 65%; niobium, 20%, tantalum, 10%; and zirconium, 5%. The TiNbTaZr alloy had a yield strength of about 550 MPa, a...

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Bibliographic Details
Published in:Doklady. Chemistry 2018-09, Vol.482 (1), p.204-206
Main Authors: Sevostyanov, M. A., Baikin, A. S., Shatova, L. A., Nasakina, E. O., Berezhnov, A. V., Gudkov, S. V., Sergienko, K. V., Konushkin, S. V., Baskakova, M. I., Kolmakov, A. G.
Format: Article
Language:English
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Summary:Titanium-based alloy with low-toxic metals such as niobium, tantalum and zirconium (TiNbTaZr) was manufactured. The primary weight percentages of elements used for fusion were: titanium, 65%; niobium, 20%, tantalum, 10%; and zirconium, 5%. The TiNbTaZr alloy had a yield strength of about 550 MPa, a tensile strength of about 700 MPa, and a Young’s modulus of about 50 GPa, that is, it was comparable with Nitinol. A primary study of the biocompatibility of the TiNbTaZr alloy using the SH-SY5Y cells showed that the alloy did not have significant short-term toxicicity towards the cells incubated on the alloy surface. The number of non-viable cells was 2.5 times lower on the TiNbTaZr alloy than on Nitinol. The biocompatibility of TiNbTaZr was more pronounced than that of the Nitinol reference sample.
ISSN:0012-5008
1608-3113
DOI:10.1134/S0012500818090045