Enzymatic glucose biosensor based on manganese dioxide nanoparticles decorated on graphene nanoribbons

• Published in: Journal of electroanalytical chemistry (Lausanne, Switzerland) Switzerland), 2018-08, Vol.823, p.610-616
• Main Authors: Vukojević, Vesna, Djurdjić, Sladjana, Ognjanović, Miloš, Fabián, Martin, Samphao, Anchalee, Kalcher, Kurt, Stanković, Dalibor M.
• Format: Article
• Language: English
• Subjects: Biosensors; Carbon; Electrical measurement; Electrodes; Glucose; Glucose biosensor; Graphene; Graphene nanoribbons; Manganese compounds; Manganese dioxide; Nanoparticles; Nanoribbons; Reproducibility; Screen printed electrodes; Silver chloride
• ISSN: 1572-6657; 1873-2569
• DOI: 10.1016/j.jelechem.2018.07.013

A disposable glucose biosensor was prepared using nanoparticles of MnO2 decorated on graphene nanoribbons by surface modification with drop coating with the GOx and Nafion®. Tested material was synthesized and characterized using several techniques. The biosensor could be operated under physiological conditions (0.1 M phosphate buffer, pH 7.4) and exhibited good reproducibility and stability. The linear range for the amperometric response of the biosensor at operating potential of +0.50 (versus Ag/AgCl) was from 0.1 to 1.4 mmol/l, with a detection limit of 0.05 mmol/l and high sensitivity of 56.32 μA/mmol cm2. Developed method was tested toward glucose quantification in real samples with satisfactory accuracy and precision. [Display omitted] •New enzymatic biosensor for the determination of glucose is proposed.•Development of a disposable biosensor based on graphene nanoribbons supported with MnO2 nanoparticles.•Satisfactory selectivity, sensitivity and precision of proposed method are obtained.