Joint Involvement in Patients with Acromegaly and the Association Between Arthropathy and Disease Remission

• Published in: Turkish journal of endocrinology and metabolism 2018, Vol.22 (2), p.7-7
• Main Authors: HALİLOĞLU, Özlem, ALÇİÇEK, Merve Nur, ÇETİNKAYA, Fırat, ŞAHİN, Serdar, POLAT KORKMAZ, Özge, UĞURLU, Serdal, KADIOĞLU, Pınar
• Format: Article
• Language: English
• Subjects: Quality of life; X-rays
• ISSN: 1301-2193; 1308-9846
• DOI: 10.25179/tjem.20182202-S31

Aim: To evaluate joint complaints, physical examinations and X-rays of acromegalic patients and investigate association between arthropathy and disease remission and effects of arthropathy on quality of life. Method: Acromegalic patients followed at Endocrinology clinic of Cerrahpasa Medical Faculty between 2015-2017 were screened. Demographic and disease status, physical examinations and quality of life scales (Acro-QoL) were recorded. The symptoms and examination findings of patients consulted with Rheumatology or Physical Therapy-Rehabilitation departments and X-rays were evaluated, retrospectively. Results: Ninety-seven patients were assessed, 38 patients (F/M:31/7; p=0.006) had joint complaints and 59 (60.8%; F/M: 40/19; p>0.05) had pathological joint findings. Pathological joint signs were found in 30 patients with no symptoms, whereas 9 out of 38 patients who declared joint symptoms had no signs at rheumatological examination. Patients with symptoms and signs were older (47.6±11.5 vs 53.3±11.9; p=0.02 and 44.3±9.1 vs 53.4±12.3; p