The Synergistic Effect of Cisplatin and Interferon β on Human Lung Adenocarcinoma Cell Line (A549)

[...]induction of apoptosis to cancer cell line may be an important mechanism and promising results of anti- tumor. [...]reduce the transcription factor which rises the sensitivity of cancer cells to the necrosis through the exploit of chemotherapeutic drugs [11]. [...]tow highest concentrations app...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2018-08, Vol.10 (8), p.1939-1942
Main Authors: Obied, Hamid Naji, Enayah, Sabah H, Ghaleb, Rana A, Obaid, Rasha F
Format: Article
Language:English
Subjects:
Apoptosis
Breast cancer
Cancer therapies
Cell cycle
Cervical cancer
Chemotherapy
Drug dosages
Interferon
Liver cancer
Lung cancer
Metastasis
Transcription factors
Tumors
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Summary:[...]induction of apoptosis to cancer cell line may be an important mechanism and promising results of anti- tumor. [...]reduce the transcription factor which rises the sensitivity of cancer cells to the necrosis through the exploit of chemotherapeutic drugs [11]. [...]tow highest concentrations applied showed low number of the cells at 24(37.04+62.96), 48(8.439+1.84) and 72h (22.63+77.37) figure (3). [...]INF- ß would synergistically, even with small dose, enhanced cell growth inhibitory impact of Cis on human lung cells that treated in combination of INF- ß and Cis for 48 and 72h.
ISSN:0975-1459