Stereotactic biopsy of the brain mass lesions: a tertiary hospital experience

• Published in: Dicle tıp dergisi 2018-09, Vol.45 (3), p.245-253
• Main Authors: Bulduk, Erkut Baha, Aslan, Ayfer, Öcal, Özgür, Emmez, Ömer Hakan, Kurt, Gökhan, Aykol, Şükrü
• Format: Article
• Language: English
• Subjects: Accuracy; Biopsy; Brain cancer; Medical imaging; Morbidity; Mortality; Neurosurgery; NMR; Nuclear magnetic resonance; Patients; Surgery; Tumors
• ISSN: 1300-2945; 1308-9889

Objectives: Stereotactic biopsy (SB) is a guided technic performed for the lesions on eloquent brain areas. The aim of this study is revealing the diagnostic reliability and the risk ratio of SB.Methods: Data of patients performed SB due to various intracranial lesions was collected retrospectively. The study took place in Department of Neurosurgery, Gazi University Faculty of Medicine between February 2004 and April 2014. Data analysis performed in terms of age, gender, lesion location, histopathology, and outcomes of surgery.Results: Sixty percent of patients were male (146 patients) and forty percent of them was female (96 patients), between the ages of 11 and 84 years (mean age of 49 years) with a total number of 242. Mortality and morbidity rates were respectively 0.4% and 3.3%. The overall diagnostic yield was 81% (196 patients), while 19% (46 patients) had nonspecific results, which did cannot lead any further therapy. Among 36 patients of whom pathologies were confirmed with an excisional biopsy, the diagnostic accuracy was shown in 24 patients (67%).Conclusions: Beside low risk of mortality and morbidity, the high rate of non-diagnostic results and low rate of diagnostic accuracy are the limitations of SB, which should be improved by careful skills to obtain more specimen, sophisticated software for planning, and intraoperative pathological examination for guaranteeing.