Loading…

Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air

A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a fe...

Full description

Saved in:

Bibliographic Details
Published in:	Technical physics 2018-10, Vol.63 (10), p.1543-1551
Main Authors:	Kogan, V., Antonov, A. S., Chichagov, Yu. V., Victorova-Leclerc, O. S., Victorov, I. V., Kozlenok, A. V.
Format:	Article
Language:	English
Subjects:	Biomarkers Classical and Continuum Physics Computer simulation Experimental Instruments and Technique Gas pressure Physics Physics and Astronomy Spectrometry VOCs Volatile organic compounds
Citations:	Items that this one cites
Online Access:	Get full text
Tags:	Add Tag No Tags, Be the first to tag this record!

cited_by
cites	cdi_FETCH-LOGICAL-c268t-878e4ec7bf529ff10c9a95c9723e8ec40c05aff6dc71affc00e99e61e8474aaf3
container_end_page	1551
container_issue	10
container_start_page	1543
container_title	Technical physics
container_volume	63
creator	Kogan, V. Antonov, A. S. Chichagov, Yu. V. Victorova-Leclerc, O. S. Victorov, I. V. Kozlenok, A. V.
description	A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.
doi_str_mv	10.1134/S1063784218100146
format	article
fullrecord	<record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_2120232324</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>2120232324</sourcerecordid><originalsourceid>FETCH-LOGICAL-c268t-878e4ec7bf529ff10c9a95c9723e8ec40c05aff6dc71affc00e99e61e8474aaf3</originalsourceid><addsrcrecordid>eNp1kM1LAzEQxYMoWKt_gLeA59VMNpvNHkutH9DiYfW8pOmk3bJfJlmw_70pFTyIzOENzO-9gUfILbB7gFQ8lMBkmivBQQFjIOQZmQArWCIznp0fd5kmx_slufJ-HxFQmZyQ8rEf1w0mK2zXTndIS90OTd1taXnwAVtad1TTlfaelgOa4PoWAzpqe0fDLuJh3Bxob-nia6cb3NBZ7a7JhdWNx5sfnZKPp8X7_CVZvj2_zmfLxHCpQqJyhQJNvrYZL6wFZgpdZKbIeYoKjWCGZdpauTE5RDWMYVGgBFQiF1rbdEruTrmD6z9H9KHa96Pr4suKA2c8jSMiBSfKuN57h7YaXN1qd6iAVcfuqj_dRQ8_eXxkuy263-T_Td-2W3AD</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>2120232324</pqid></control><display><type>article</type><title>Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air</title><source>Springer Nature</source><creator>Kogan, V. ; Antonov, A. S. ; Chichagov, Yu. V. ; Victorova-Leclerc, O. S. ; Victorov, I. V. ; Kozlenok, A. V.</creator><creatorcontrib>Kogan, V. ; Antonov, A. S. ; Chichagov, Yu. V. ; Victorova-Leclerc, O. S. ; Victorov, I. V. ; Kozlenok, A. V.</creatorcontrib><description>A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.</description><identifier>ISSN: 1063-7842</identifier><identifier>EISSN: 1090-6525</identifier><identifier>DOI: 10.1134/S1063784218100146</identifier><language>eng</language><publisher>Moscow: Pleiades Publishing</publisher><subject>Biomarkers ; Classical and Continuum Physics ; Computer simulation ; Experimental Instruments and Technique ; Gas pressure ; Physics ; Physics and Astronomy ; Spectrometry ; VOCs ; Volatile organic compounds</subject><ispartof>Technical physics, 2018-10, Vol.63 (10), p.1543-1551</ispartof><rights>Pleiades Publishing, Ltd. 2018</rights><rights>Copyright Springer Science & Business Media 2018</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><cites>FETCH-LOGICAL-c268t-878e4ec7bf529ff10c9a95c9723e8ec40c05aff6dc71affc00e99e61e8474aaf3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids></links><search><creatorcontrib>Kogan, V.</creatorcontrib><creatorcontrib>Antonov, A. S.</creatorcontrib><creatorcontrib>Chichagov, Yu. V.</creatorcontrib><creatorcontrib>Victorova-Leclerc, O. S.</creatorcontrib><creatorcontrib>Victorov, I. V.</creatorcontrib><creatorcontrib>Kozlenok, A. V.</creatorcontrib><title>Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air</title><title>Technical physics</title><addtitle>Tech. Phys</addtitle><description>A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.</description><subject>Biomarkers</subject><subject>Classical and Continuum Physics</subject><subject>Computer simulation</subject><subject>Experimental Instruments and Technique</subject><subject>Gas pressure</subject><subject>Physics</subject><subject>Physics and Astronomy</subject><subject>Spectrometry</subject><subject>VOCs</subject><subject>Volatile organic compounds</subject><issn>1063-7842</issn><issn>1090-6525</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2018</creationdate><recordtype>article</recordtype><recordid>eNp1kM1LAzEQxYMoWKt_gLeA59VMNpvNHkutH9DiYfW8pOmk3bJfJlmw_70pFTyIzOENzO-9gUfILbB7gFQ8lMBkmivBQQFjIOQZmQArWCIznp0fd5kmx_slufJ-HxFQmZyQ8rEf1w0mK2zXTndIS90OTd1taXnwAVtad1TTlfaelgOa4PoWAzpqe0fDLuJh3Bxob-nia6cb3NBZ7a7JhdWNx5sfnZKPp8X7_CVZvj2_zmfLxHCpQqJyhQJNvrYZL6wFZgpdZKbIeYoKjWCGZdpauTE5RDWMYVGgBFQiF1rbdEruTrmD6z9H9KHa96Pr4suKA2c8jSMiBSfKuN57h7YaXN1qd6iAVcfuqj_dRQ8_eXxkuy263-T_Td-2W3AD</recordid><startdate>20181001</startdate><enddate>20181001</enddate><creator>Kogan, V.</creator><creator>Antonov, A. S.</creator><creator>Chichagov, Yu. V.</creator><creator>Victorova-Leclerc, O. S.</creator><creator>Victorov, I. V.</creator><creator>Kozlenok, A. V.</creator><general>Pleiades Publishing</general><general>Springer Nature B.V</general><scope>AAYXX</scope><scope>CITATION</scope></search><sort><creationdate>20181001</creationdate><title>Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air</title><author>Kogan, V. ; Antonov, A. S. ; Chichagov, Yu. V. ; Victorova-Leclerc, O. S. ; Victorov, I. V. ; Kozlenok, A. V.</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c268t-878e4ec7bf529ff10c9a95c9723e8ec40c05aff6dc71affc00e99e61e8474aaf3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2018</creationdate><topic>Biomarkers</topic><topic>Classical and Continuum Physics</topic><topic>Computer simulation</topic><topic>Experimental Instruments and Technique</topic><topic>Gas pressure</topic><topic>Physics</topic><topic>Physics and Astronomy</topic><topic>Spectrometry</topic><topic>VOCs</topic><topic>Volatile organic compounds</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>Kogan, V.</creatorcontrib><creatorcontrib>Antonov, A. S.</creatorcontrib><creatorcontrib>Chichagov, Yu. V.</creatorcontrib><creatorcontrib>Victorova-Leclerc, O. S.</creatorcontrib><creatorcontrib>Victorov, I. V.</creatorcontrib><creatorcontrib>Kozlenok, A. V.</creatorcontrib><collection>CrossRef</collection><jtitle>Technical physics</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>Kogan, V.</au><au>Antonov, A. S.</au><au>Chichagov, Yu. V.</au><au>Victorova-Leclerc, O. S.</au><au>Victorov, I. V.</au><au>Kozlenok, A. V.</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air</atitle><jtitle>Technical physics</jtitle><stitle>Tech. Phys</stitle><date>2018-10-01</date><risdate>2018</risdate><volume>63</volume><issue>10</issue><spage>1543</spage><epage>1551</epage><pages>1543-1551</pages><issn>1063-7842</issn><eissn>1090-6525</eissn><abstract>A double-membrane sample-introduction system is described that enables mass spectrometric determination of volatile organic compounds in air, while ensuring their detection limits are as low as a few fractions of ppb of sample composition in real time with a response delay from a few seconds to a few dozens of seconds. It includes two membrane interfaces separated by a volume, the gas pressure in which is maintained through a channel with an adjustable evacuation cross-section. The results of numerical simulation and experimental testing of the system are provided. A technique for selecting and calculating system parameters is described. The possibility of using this system for diagnosing diseases by trace amounts of biomarkers in exhaled air is discussed.</abstract><cop>Moscow</cop><pub>Pleiades Publishing</pub><doi>10.1134/S1063784218100146</doi><tpages>9</tpages></addata></record>
fulltext	fulltext
identifier	ISSN: 1063-7842
ispartof	Technical physics, 2018-10, Vol.63 (10), p.1543-1551
issn	1063-7842 1090-6525
language	eng
recordid	cdi_proquest_journals_2120232324
source	Springer Nature
subjects	Biomarkers Classical and Continuum Physics Computer simulation Experimental Instruments and Technique Gas pressure Physics Physics and Astronomy Spectrometry VOCs Volatile organic compounds
title	Double-Membrane Sampling System in a Mass Spectrometer for the Study of Exhaled Air
url	http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-27T13%3A40%3A36IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Double-Membrane%20Sampling%20System%20in%20a%20Mass%20Spectrometer%20for%20the%20Study%20of%20Exhaled%20Air&rft.jtitle=Technical%20physics&rft.au=Kogan,%20V.&rft.date=2018-10-01&rft.volume=63&rft.issue=10&rft.spage=1543&rft.epage=1551&rft.pages=1543-1551&rft.issn=1063-7842&rft.eissn=1090-6525&rft_id=info:doi/10.1134/S1063784218100146&rft_dat=%3Cproquest_cross%3E2120232324%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c268t-878e4ec7bf529ff10c9a95c9723e8ec40c05aff6dc71affc00e99e61e8474aaf3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=2120232324&rft_id=info:pmid/&rfr_iscdi=true