Poly Phosphoric Acid Impregnated on Silica Gel (PPA-SiO2): A Versatile and Reusable Catalyst for the Synthesis of 1,2,4,5-Tetrasubstituted Imidazoles under Solvent-free and Microwave Irradiation Conditions

A remarkable acceleration in the synthesis of 1,2,4,5-tetrasubstituted imidazoles catalyzed by silica gel supported poly phosphoric acid in high yields under solvent-free and microwave irradiation conditions, with very short reaction time is described. This methodology offers momentous improvements...

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Bibliographic Details
Published in:Oriental journal of chemistry 2011-01, Vol.27 (3), p.1023
Main Authors: Montazeri, Naser, Khalil Pourshamsian, Khoddadi, Marjan, Khoddadi, Kazem
Format: Article
Language:English
Subjects:
Catalysis
Catalysts
Chemical synthesis
Irradiation
Phosphoric acid
Reaction time
Silica gel
Silicon dioxide
Solvents
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Summary:A remarkable acceleration in the synthesis of 1,2,4,5-tetrasubstituted imidazoles catalyzed by silica gel supported poly phosphoric acid in high yields under solvent-free and microwave irradiation conditions, with very short reaction time is described. This methodology offers momentous improvements over various options for the synthesis of 1,2,4,5-tetrasubstituted imidazoles with regard to yield of produces, simplicity in operation and green aspects by avoiding toxic catalysts and solvents.
ISSN:0970-020X
2231-5039