Synthesis of 5-(Substitutedphenyl)-{3-[4-(2-Methyl-4-(4-Hydroxy Benzylidene)-5-Oxo-Imidazol-1-Yl)]Phenyl} -Isoxazol and Study of the Antimicrobial Activities

5-(substitutedphenyl)-{3-[4-(2-methyl-4-(4-hydroxy benzylidene)-5-oxo-imidazol-1-yl)]phenyl}-isoxazol have been prepared by the refluxation for ten hours of 4-(4-hydroxybenzylidene)-1-{4-[3-(stituted phenyl)prop-2-enoyl]phenyl}-2-methyl-imidazol-5-one with hydroxylamine hydrochloride and 40% potassi...

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Bibliographic Details
Published in:Oriental journal of chemistry 2009-01, Vol.25 (1), p.111
Main Authors: Patel, P S, Shah, R A, Trivedi, D K, Vyas, P J
Format: Article
Language:English
Subjects:
Aldehydes
Potassium hydroxides
Online Access:Get full text
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Summary:5-(substitutedphenyl)-{3-[4-(2-methyl-4-(4-hydroxy benzylidene)-5-oxo-imidazol-1-yl)]phenyl}-isoxazol have been prepared by the refluxation for ten hours of 4-(4-hydroxybenzylidene)-1-{4-[3-(stituted phenyl)prop-2-enoyl]phenyl}-2-methyl-imidazol-5-one with hydroxylamine hydrochloride and 40% potassium hydroxide in presence of dioxane. The intermidiate 4-(4-hydroxybenzylidene)-1-{4-[3-(stituted phenyl)prop-2-enoyl]phenyl}-2-methyl-imidazol-5-one synthesized by the condensation of 1-(4-acetylphenyl)-4-(4-hydroxybenzylidene)-2-methyl-3,5-dihydro-imidazol-5-one with various aldehydes.
ISSN:0970-020X
2231-5039