Carbapenems, Linezolid, Teicoplanin Utilization Evaluation in a Large Teaching Based Hospital (Shahid Rajaie Heart Center, Tehran): A Quality Improvement Study

The Aim of this study is to access the number of inappropriate usages of post CABG antibiotics such as, Carbapenems, Teicoplanin and Linezolid in Shahid Rajaie Hospital and to apply antibiotic practice guidelines and strategies to reduce inadequate treatment while determining their impact on patient...

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Bibliographic Details
Published in:Biomedical & pharmacology journal 2016, Vol.9 (2), p.525-532
Main Authors: Fariborz Farsad, Bahram, Hadavand, Naser, Salehi, Hanieh, Shekari, Masoumeh
Format: Article
Language:English
Subjects:
Antibiotics
Antimicrobial agents
Carbapenems
Cardiovascular disease
Drug dosages
Drug resistance
Family medical history
Heart
Heart surgery
Imipenem
Kidney diseases
Linezolid
Medical records
Meropenem
Patients
Pharmaceuticals
Prescription drugs
Quality control
Sepsis
Skin
Studies
Substance abuse treatment
Teicoplanin
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Summary:The Aim of this study is to access the number of inappropriate usages of post CABG antibiotics such as, Carbapenems, Teicoplanin and Linezolid in Shahid Rajaie Hospital and to apply antibiotic practice guidelines and strategies to reduce inadequate treatment while determining their impact on patient outcomes. This retrospective study was performed at special wards of Shahid Rajaie Hospital. The program was conducted since March to August 2015. All of the patients which were on Imipenem, Meropenem, Linezolide or Teicoplanin as an empiric treatment or based on culture results were considered in the study. The results of this study indicated that among 136 in-patients who had taken at least one of these antibiotics including Imipenem, Meropenem, Linezolide or Teicoplanin, antimicrobial prescription assumed inappropriate for 63 patients (46.32%), The most common reason was incorrect dosage (16.39%)and the least one was not being drug of choice(2.4%).this inappropriateness was occurred mostly in diagnosis of respiratory infection , skin infection and sepsis. The results of this study demonstrates the need for revision in program of prescribing antibiotics in the direction of using antibiotic practice guidelines especially regarding usage of Teicoplanin and Meropenem in specific complication such as respiratory infection and skin infection.
ISSN:0974-6242
2456-2610
DOI:10.13005/bpj/968