Comparison of Antibiotic Prophylaxis Prescription Prior to Surgery Operations with National Instruction

• Published in: Biomedical & pharmacology journal 2016, Vol.9 (1), p.253-258
• Main Authors: AHMADI, MOSSA, SHOKOUH, SEYYED
• Format: Article
• Language: English
• Subjects: Ambulatory care; Antibiotics; Cephalosporins; Disease control; Epidemiology; Gynecology; Health care; Hospitals; Hygiene; Industrialized nations; Infectious diseases; Metronidazole; Mortality; Neurosurgery; Nosocomial infections; Patients; Preventive medicine; Prophylaxis; Staphylococcus infections; Statistical analysis; Surgeons; Surgery; Surveillance
• ISSN: 0974-6242; 2456-2610
• DOI: 10.13005/bpj/933

Inappropriate use of AB in surgeries may result in AB resistance and increased costs. Hence, we performed this study to evaluate the congruence of prescribed AB for prophylaxis before surgery with those recommended by heath ministry and army hospitals in 2009. A random sample of patients (from Cardiosurgeri, Gynecology, General surgery, Urology and Neurosurgery) in army hospitals was selected and the age, sex, AB duration, physician specialty and type and dose of AB were evaluated; if it was completely in congruence with recommendation of health ministry or not. The descriptive, central and distribution results were shown. The mean age of patients was 38.7 years and 43.7% were male. Cephalosporin, metronidazole, and aminoglycosides were prescribed 81.3%, 19.5% and 10.8% of patients respectively. For most of cases (80.3%) AB treatment period was shorter than 24 hours. Cephalosporins and Metronidazole were prescribed mostly by general surgeons (91.2% and 57% respectively) and Aminoglycosides were prescribed mostly by Gynecologist (91.2%). The prescription frequency based on physician specialty were statistically significant for all studied antibiotics. There was congruence in 79.5% in prescription, in 4.6% in AB type and in 48.2% AB treatment period. Totally 83.6% had no congruence with recommendation of health ministry. Excess and inappropriate use of AB for preoperative prophylaxis had a high rate in understudy hospitals. Therefore it is strongly recommended to pay more attention to physicians’ education about AB and the AB prescription supervisory committees and hospital infection committees act more active.