The Effect of Hydro Alcoholic Cinnamon Extract on Changes of Gonadotropins (LH and FSH) in Mice Treated with Co-codamol

Cinnamon with scientific name of Cinnamomum Zeylanicum Nees and common name of Cinnamon is aromatic and pleasant plant. The treatment plant has anti spasmodic, carminative, anti-diarrhea, anti-bacterial, anti-parasitic, and cooling effects. Due to the possible side effects of Co-codamol on the body...

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Bibliographic Details
Published in:Biomedical & pharmacology journal 2014-06, Vol.7 (1), p.369-373
Main Authors: Mohammad, Pourahmad, Liela, Golami, Mohsen, Farzam, Hossein, Kargar Jahromi
Format: Article
Language:English
Subjects:
Alcohol
Antioxidants
Arthritis
Cinnamon
Diarrhea
Disease
Drug dosages
Drug resistance
Enzyme-linked immunosorbent assay
Flavonoids
Follicle-stimulating hormone
Gonadotropins
Laboratories
Luteinizing hormone
Nonsteroidal anti-inflammatory drugs
Pain
Pharmaceutical industry
Physiology
Pituitary (anterior)
Side effects
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Summary:Cinnamon with scientific name of Cinnamomum Zeylanicum Nees and common name of Cinnamon is aromatic and pleasant plant. The treatment plant has anti spasmodic, carminative, anti-diarrhea, anti-bacterial, anti-parasitic, and cooling effects. Due to the possible side effects of Co-codamol on the body and cinnamon benefits, the current study seeks to investigate the possible effects of cinnamon on Co-codamol complications. 42 female Wistar rats were randomly divided into 7 groups. The first group (control group) did not receive any medication. Experimental group 1 received a dose of 50 mg / kg cinnamon, experimental group 2 received, 200 mg / kg cinnamon, experimental group 3 received, 400 mg / kg Co-codamol alone, experimental groups 4 and 5; in addition Co-codamol medicine received 50 mg / kg and 400 mg / kg cinnamon intraperitoneally. At the end of 21 days, blood samples were prepared from the rats and the LH and FSH serum concentrations were measured by ELISA. The data is then tested by ANOVA (One-way analysis of variance) at a significance level (P
ISSN:0974-6242
2456-2610
DOI:10.13005/bpj/500