Design, synthesis and radical scavenging performance of 2,2’-(4,5-dihydro-1H-pyrazol-3,5-dyl) diphenol

Heterogeneous catalytic synthesis of a pyrazoline derivative, 2,2’-(4,5-dihydro-1H-pyrazol-3,5-dyl)diphenol from the reaction between (E)-1,3-bis(2-hydroxyphenyl)prop-2-en-1-one and hydrazine hydrate has been done using sodium impregnated on the activated chicken eggshells (Na-ACE). The agreement of...

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Bibliographic Details
Main Authors: Ardiansah, B., Mardiana, L., Bakri, R., Aziza, N. P., Baramanda, T. A.
Format: Conference Proceeding
Language:English
Subjects:
Catalysis
Chemical synthesis
Diphenols
Ethanol
Free radicals
Hydrazines
Scavenging
Sodium
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Summary:Heterogeneous catalytic synthesis of a pyrazoline derivative, 2,2’-(4,5-dihydro-1H-pyrazol-3,5-dyl)diphenol from the reaction between (E)-1,3-bis(2-hydroxyphenyl)prop-2-en-1-one and hydrazine hydrate has been done using sodium impregnated on the activated chicken eggshells (Na-ACE). The agreement of the product structure was confirmed using FTIR, UV-Vis, and LC-ESI-MS instruments. This pyrazoline derivative has a significant activity to scavenge free radical of DPPH model in ethanol solution.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.5064083