History of the Plaster-Based Drug Formulations' Development

According to the same source, plasters based on dog's-tongue, hyoscyamus and tobacco were used as an analgesic and sedative agent. The active substances that determine the pharmacological activity of the drug enter the systemic circulation, penetrating through the skin or mucous membrane due to...

Full description

Saved in:
Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2018-09, Vol.10 (9), p.2212-2215
Main Authors: Krylova, O V, Litvinova, T M, Babaskin, D V, Udovichenko, E V, Winter, E A
Format: Article
Language:English
Subjects:
20th century
Ancient civilizations
Avicenna (980-1037)
Content analysis
Drug dosages
Egyptian civilization
Evolution
Hippocrates (460?-377? BC)
Insulin
Medicine
Modernization
Pharmaceutical industry
Skin
Vaccines
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:According to the same source, plasters based on dog's-tongue, hyoscyamus and tobacco were used as an analgesic and sedative agent. The active substances that determine the pharmacological activity of the drug enter the systemic circulation, penetrating through the skin or mucous membrane due to the concentration gradient on both sides of the semipermeable membrane, which, in this case, is represented by the skin or mucous membrane. Conclusions The systematization and analysis of scientific and literary sources allowed determining that the plaster-based drug formulations had undergone significant evolution due to changes in their composition, modernization of external forms and production technologies, improvement of consumer properties, and an increase in quality. Belousov, Yu.B., Bukhman, V.M., Erofeyeva, S.B., Leonova, M.V., Maneshina, O.A., Mukhina, M.A., Strok, A.B., Lekarstvennyye formy s modifitsirovannym vysvobozhdeniyem i sistemy dostavki lekarstv: osobennosti farmakokinetiki i klinicheskaya effektivnost' [Modified release dosage forms and drug delivery systems: features of pharmacokinetics and clinical efficacy.], Litterra, Moscow 2011.
ISSN:0975-1459