In vivo bio-imaging studies of highly selective, sensitive rhodamine based fluorescent chemosensor for the detection of Cu^sup 2+^/Fe^sup 3+^ ions

• Published in: Sensors and actuators. B, Chemical Chemical, 2018-11, Vol.B274, p.22
• Main Authors: Murugan, A Senthil, Vidhyalakshmi, N, Ramesh, U, Annaraj, J
• Format: Article
• Language: English
• Subjects: Calcium ions; Chemical sensors; Chemoreceptors; Cobalt; Copper; Embryos; Ferric ions; Ferrous ions; Fluorescence; In vivo methods and tests; Ions; Lead; Manganese; Mercury (metal); Metal ions; Nickel; Quinoline; Rhodamine; Sensors; Transition metals; Zebrafish
• ISSN: 0925-4005; 1873-3077

A Rhodamine based quinoline conjugated fluorescence chemosensor (RhQA) was delineated for the detection of two paramagnetic metal ions (Fe3+/Cu2+) through various analytical techniques. The addition of Fe3+ and Cu2+ ions induced a great enhancement in the absorption of RhQA; moreover, Fe3+ also induced a strong fluorescence enhancement. Hence, this is an admirable example for the selective detection of the biologically/environmentally significant transition metal ions as dual chemosensor. The obtained results reveal that the chemosensor (RhQA) has remarkable selectivity towards Fe3+/Cu2+ ions even in the presence of higher concentration of various interference metal ions such as Pb2+, Cd2+, Hg2+, Zn2+, Ni2+, Co2+, Mn2+, Fe2+, Cr3+, Ca2+, Ba2+, Mg2+, Na+, K+, and Ag+. Its excellency in sensitivity was confirmed by the obtained linear relationship with Fe2+/Cu3+ ions, and the calculated detection limit values are, 1.8 × 10−8 and 3.3 × 10−8 M for Cu2+ and Fe3+ ions respectively. More interestingly, this chemosensor, RhQA was successfully employed to trace out the intra cellular Fe3+ ions in Zebrafish embryos.