Fatal Poisoning with Both Dichlorvos and Phenthoate

Organophosphates are widely used as pesticides. However, organophosphates are occasionally orally ingested to commit suicide. In this case, a man in his late 80s committed suicide by ingesting both dichlorvos and phenthoate. Autopsy findings revealed a characteristic volatile odor from his mouth, st...

Full description

Saved in:
Bibliographic Details
Published in:Journal of forensic sciences 2018-11, Vol.63 (6), p.1928-1931
Main Authors: Nara, Akina, Yamada, Chiho, Kodama, Takanori, Saka, Kanju, Takagi, Tetsuya
Format: Article
Language:English
Subjects:
Aged, 80 and over
Autopsies
carboxylesterase
Cholinesterase
cholinesterase activity
dichlorvos
Dichlorvos - adverse effects
Dichlorvos - analysis
Elasticity
forensic science
forensic toxicology
Gastrointestinal Contents - chemistry
Health risk assessment
Humans
Ingestion
Kidneys
Liquid chromatography
Liver
Lungs
Male
Mass spectrometry
organophosphate
Organophosphate Poisoning
Organophosphates
Organothiophosphorus Compounds - analysis
Organothiophosphorus Compounds - poisoning
Pesticides
phenthoate
Poisoning
Stomach
Suicide
Suicides & suicide attempts
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Organophosphates are widely used as pesticides. However, organophosphates are occasionally orally ingested to commit suicide. In this case, a man in his late 80s committed suicide by ingesting both dichlorvos and phenthoate. Autopsy findings revealed a characteristic volatile odor from his mouth, stomach, lungs, liver, and kidneys. The esophageal mucosa was denatured and had lost elasticity. Serum cholinesterase activity was 9 IU/L. Toxicological analyses performed using high‐performance liquid chromatography–tandem mass spectrometry revealed that dichlorvos concentrations in the left and right cardiac blood samples were 11.6 and 4.6 μg/mL, respectively. Phenthoate concentrations in the left and right cardiac blood samples were 5.8 and 0.51 μg/mL, respectively. The total amounts of dichlorvos and phenthoate in the stomach were 7.35 and 4.55 g, respectively. The case history, autopsy findings, and toxicological analyses indicated that the cause of death was acute fatal poisoning after oral ingestion of both dichlorvos and phenthoate.
ISSN:0022-1198
1556-4029
DOI:10.1111/1556-4029.13781