Risks of unfavourable clinical outcomes in patients with first diagnosed stroke-associated atrial fibrillation

• Published in: Journal of pharmaceutical sciences and research 2018-10, Vol.10 (10), p.2431-2434
• Main Authors: Zolotovskaya, I A, Duplyakov, D V, Svistunov, A A, Davydkin, I L, Osadchuk, A M, Osadchuk, M A, Trushin, M V
• Format: Article
• Language: English
• Subjects: Age; Anticoagulants; Cardiac arrhythmia; Cardiology; Cardiovascular disease; Clinical medicine; Clinical outcomes; Diabetes; Health risk assessment; Heart; Hypertension; Kidney diseases; Medical prognosis; Mortality; Multivariate analysis; Neurological disorders; Patients; Stroke; Studies; Task forces; Values
• ISSN: 0975-1459

According to our data, the age, HAS-BLED score, and hypertension and ischemic heart disease incidence rates of patients with fdAF were comparable with the rest of the group. According to death certificates, 69 (65.1%) patients died from recurrent acute cerebrovascular event, in 17 (16.0%) patients death occurred due to myocardial infarction, in 4 (3.8%) patients - due to malignant tumor, in one (0.9%) patient- due to acute kidney injury, and in 15 (14.2%) patients death was considered sudden. According to Kaplan-Meier analysis (Figure 1) the highest death rate during one year was observed in the group of patients with fdAF. According to the results of the multivariate Cox regression analysis (Table 4), in the group of patients with fdAF mortality hazards are associated with stroke severity and the history of ischemic heart disease, chronic heart failure or chronic kidney disease.