Alcohol and smoking as risk factors in chronic pancreatitis and pancreatic cancer

The aim of this study was to compare alcohol and smoking as risk factors in the development of chronic pancreatitis and pancreatic cancer. We considered only male subjects: (1) 630 patients with chronic pancreatitis who developed 12 pancreatic and 47 extrapancreatic cancers; (2) 69 patients with his...

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Bibliographic Details
Published in:Digestive diseases and sciences 1999-07, Vol.44 (7), p.1303-1311
Main Authors: TALAMINI, G, BASSI, C, VAONA, B, ANGELINI, G, VANTINI, I, CAVALLINI, G, PEDERZOLI, P, FALCONI, M, SARTORI, N, SALVIA, R, RIGO, L, CASTAGNINI, A, DI FRANCESCO, V, FRULLONI, L, BOVO, P
Format: Article
Language:English
Subjects:
Adenocarcinoma - etiology
Adult
Aged
Alcohol Drinking - adverse effects
Biological and medical sciences
Chronic Disease
Cocarcinogenesis
Follow-Up Studies
Gastroenterology. Liver. Pancreas. Abdomen
Humans
Liver. Biliary tract. Portal circulation. Exocrine pancreas
Male
Medical sciences
Middle Aged
Neoplasms, Multiple Primary - etiology
Pancreatic cancer
Pancreatic Neoplasms - etiology
Pancreatitis - etiology
Pancreatitis, Alcoholic - etiology
Prospective Studies
Risk Factors
Smoking - adverse effects
Tumors
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Summary:The aim of this study was to compare alcohol and smoking as risk factors in the development of chronic pancreatitis and pancreatic cancer. We considered only male subjects: (1) 630 patients with chronic pancreatitis who developed 12 pancreatic and 47 extrapancreatic cancers; (2) 69 patients with histologically well documented pancreatic cancer and no clinical history of chronic pancreatitis; and (3) 700 random controls taken from the Verona polling list and submitted to a complete medical check-up. Chronic pancreatitis subjects drink more than control subjects and more than subjects with pancreatic cancer without chronic pancreatitis (P
ISSN:0163-2116
1573-2568
DOI:10.1023/a:1026670911955