Clusters and Clustering of Childhood Cancer: A Review

Methodological considerations in the study of clusters and clustering of childhood cancer are reviewed briefly. A selection of 11 studies of individual clusters of childhood leukaemia which are either particularly notable or recent and have been reported in peer review journals is then considered. F...

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Bibliographic Details
Published in:European journal of epidemiology 1999-10, Vol.15 (9), p.847-852
Main Author: Alexander, Freda E.
Format: Article
Language:English
Subjects:
Adolescent
Adult
Age Distribution
Biological and medical sciences
Cancer
Case control studies
Child
Child, Preschool
Childhood
Children
Cluster Analysis
Datasets
Environmental Exposure - adverse effects
Epidemiologic Methods
Epidemiology
Etiology
EUROCAT, European Workshop on the Detection and Management of Clusters in Europe
General aspects
Humans
Incidence
Infant
Infant, Newborn
Leukemia
Leukemia - epidemiology
Leukemia - etiology
Lymphoma, Non-Hodgkin - epidemiology
Lymphoma, Non-Hodgkin - etiology
Medical sciences
Methodology
Non Hodgkin lymphoma
Nuclear Energy
Population Surveillance
Power Plants
Public health. Hygiene
Public health. Hygiene-occupational medicine
Spacetime
Water Pollution - adverse effects
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Description
Summary:Methodological considerations in the study of clusters and clustering of childhood cancer are reviewed briefly. A selection of 11 studies of individual clusters of childhood leukaemia which are either particularly notable or recent and have been reported in peer review journals is then considered. Focus is placed on sources of alerts, descriptive studies, field-work studies, conclusions and communication management. Some of these studies are probably essential but they are unlikely to yield firm conclusions; studies of large data sets are recommended. No causal factor has been identified which can explain a single cluster of childhood leukaemia.
ISSN:0393-2990
1573-7284
DOI:10.1023/A:1007574016008