Dietary lipid intake influences the level of cholesterol bound to haemoglobin in human erythrocytes

Background Blood cholesterol levels are affected by diet and in particular by the type of fat intake. We originally showed that a significant but variable amount of cholesterol is firmly bound to haemoglobin (Hb) yielding the Hb-lipid adduct (Hb-Ch) in erythrocytes isolated from normo-lipidemic male...

Full description

Saved in:
Bibliographic Details
Published in:European journal of nutrition 2008-04, Vol.47 (3), p.123-130
Main Authors: Nikolic, Milan, Ristic Medic, Danijela, Stanic, Dragana, Postic, Marija, Arsic, Aleksandra, Niketic, Vesna
Format: Article
Language:English
Subjects:
Adult
Biological and medical sciences
Chemistry
Chemistry and Materials Science
Cholesterol - blood
Cholesterol - metabolism
Cholesterol, HDL - blood
Cholesterol, LDL - blood
Diet, Fat-Restricted
Dietary Fats - administration & dosage
Dietary Fats - pharmacology
Dose-Response Relationship, Drug
Erythrocytes - chemistry
Erythrocytes - metabolism
Feeding. Feeding behavior
Female
Fundamental and applied biological sciences. Psychology
Hemoglobins - metabolism
Humans
Hypercholesterolemia - blood
Hypercholesterolemia - diet therapy
Male
Nutrition
Original Contribution
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Background Blood cholesterol levels are affected by diet and in particular by the type of fat intake. We originally showed that a significant but variable amount of cholesterol is firmly bound to haemoglobin (Hb) yielding the Hb-lipid adduct (Hb-Ch) in erythrocytes isolated from normo-lipidemic males. Aim of the study To establish whether dietary lipids affect the level of Hb-Ch in human erythrocytes. Methods Seventy-four healthy free-living adults were separated according to their serum cholesterol levels into two groups: normo-cholesterolemic (LDL cholesterol
ISSN:1436-6207
1436-6215
DOI:10.1007/s00394-008-0705-z