A nanozyme tag enabled chemiluminescence imaging immunoassay for multiplexed cytokine monitoring

We report a new concept of a chemiluminescence imaging nanozyme immunoassay (CINIA), in which nanozymes are exploited as catalytic tags for simultaneous multiplex detection of cytokines. The CINIA provides a novel and universal nanozyme-labeled multiplex immunoassay strategy for high-throughput dete...

Full description

Saved in:
Bibliographic Details
Published in:Chemical communications (Cambridge, England) England), 2018-12, Vol.54 (98), p.13813-13816
Main Authors: Zhong, Yihong, Tang, Xiao, Li, Juan, Lan, Qingchun, Min, Lingfeng, Ren, Chuanli, Hu, Xiaoya, Torrente-Rodríguez, Rebeca M, Gao, Wei, Yang, Zhanjun
Format: Article
Language:English
Subjects:
Animals
Antibodies, Immobilized - chemistry
Biomarkers
Catalysis
Chemiluminescence
Chickens
Copper - chemistry
Cytokines
Cytokines - analysis
Cytokines - blood
Equipment Design
High-Throughput Screening Assays - instrumentation
High-Throughput Screening Assays - methods
Immunoassay
Immunoassay - instrumentation
Immunoassay - methods
Luminescent Measurements - instrumentation
Luminescent Measurements - methods
Medical imaging
Multiplexing
Nanoparticles - chemistry
Organic chemistry
Sulfides - chemistry
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:We report a new concept of a chemiluminescence imaging nanozyme immunoassay (CINIA), in which nanozymes are exploited as catalytic tags for simultaneous multiplex detection of cytokines. The CINIA provides a novel and universal nanozyme-labeled multiplex immunoassay strategy for high-throughput detection of relevant biomarkers and further disease diagnosis. We propose a new concept of a chemiluminescence imaging nanozyme immunoassay (CINIA), in which nanozymes are exploited as catalytic tags for simultaneous and high-throughput multiplex detection of cytokines.
ISSN:1359-7345
1364-548X
DOI:10.1039/c8cc07779g