Multi-modal Aedes aegypti mosquito reduction interventions and dengue fever prevention

• Published in: Tropical medicine & international health 2009-12, Vol.14 (12), p.1542-1551
• Main Authors: Ballenger-Browning, Kara K, Elder, John P
• Format: Article
• Language: English
• Subjects: Aedes; Aedes aegypti; Animals; Arboviroses; Biological and medical sciences; Clinical Trials as Topic; control vectorial; dengue; Dengue - epidemiology; Dengue - prevention & control; Dengue - transmission; Dengue fever; Dengue fevers; Disease Reservoirs; Effectiveness studies; Entomology - methods; Environmental Monitoring - methods; Epidemiological Monitoring; General aspects; Human viral diseases; Humans; Infectious diseases; Insect control; lutte antivectorielle; Medical sciences; Mosquito Control - methods; Mosquitoes; Prevention programs; review; revisión; revue; Systematic review; Tropical viral diseases; vector control; Viral diseases
• ISSN: 1360-2276; 1365-3156
• DOI: 10.1111/j.1365-3156.2009.02396.x

To systematically review the effectiveness of biological, chemical and educational dengue fever prevention programs on the reduction of entomologic indicators. Searches of PubMed, GoogleScholar, CabDirect databases and reference lists yielded over 1000 articles containing mosquito abatement interventions. Inclusion criteria were: Vector control programs targeting Aedes aegypti and Aedes albopictus mosquitoes; Studies providing pre- and post-test data. Intervention effectiveness was assessed using Mulla's formula to determine percent reductions for all studies with control groups. Twenty-one studies were reviewed. Twelve dependent variables were presented, however, the Breteau, House and Container indices were the primary measurement tools for monitoring larval populations. Behavioural methods consisting of educational campaigns and maintaining water containers to reduce the mosquito population were applied in eight studies. Eight studies involved the use of biological methods such as predatory organisms or bacteria. Finally, eight studies used chemical control techniques including insecticide sprays, larvicides, insecticide-treated materials, and cleaning water of containers with household chemicals with three studies using a combination of intervention techniques. Post-intervention reduction in entomologic indices ranged from 100% to an increase of 13.9% from baseline. Little evidence exists to support the efficacy of mosquito abatement programs owing to poor study designs and lack of congruent entomologic indices. Creation of a standard entomological index, use of clustered and randomized-controlled trials, and testing the generalizability of proven methods are recommended for future research.