The association between clinical and pathological features in histologically identified chronic endometritis

• Published in: Journal of obstetrics and gynaecology 2004-10, Vol.24 (7), p.801-803
• Main Author: Heatley, MK
• Format: Article
• Language: English
• Subjects: Adult; Anti-Bacterial Agents - administration & dosage; Cells; Endometritis - diagnosis; Endometritis - pathology; Endometrium - pathology; Eosinophils - pathology; Female; Gynecology; Humans; Lymphocytes - pathology; Medical disorders; Menorrhagia; Middle Aged; Neutrophils - pathology; Pathology; Pelvic Pain; Plasma; Plasma Cells - pathology; Postmenopause; Reproductive system; Uterine Hemorrhage - pathology; Vaginal Discharge
• ISSN: 0144-3615; 1364-6893
• DOI: 10.1080/01443610400009550

Although described originally as the sine qua non for endometriosis, plasma cells have been identified in the endometrium in a variety of other situations. This study of patients who did and did not have plasma cells in their endometrium was carried out to establish the association between the clinical presentations and a variety of pathological characteristics, particularly the presence of inflammatory cells including plasma cells in the endometrium. There was no evidence of an association between any of the presenting clinical conditions and the distribution, intensity or frequency of inflammation, including the component cell types (lymphocytes, eosinophils, plasma cells and neutrophil polymorphs) or stromal pigment, although there was an association between a history of abnormal bleeding and reactive changes in the surface endometrium (P = 0.0259). Thus this study confirms the findings of others that there is no specific clinical syndrome that is associated with the presence of plasma cells in the endometrium.