Probiotics: Biofilm‐Inspired Encapsulation of Probiotics for the Treatment of Complex Infections (Adv. Mater. 51/2018)

In article number 1803925, Robert Langer, Ana Jaklenec, and co‐workers demonstrate a biofilm‐inspired encapsulation of probiotics using alginate to confer temporary antibiotic protection to susceptible probiotics. This enables the coadministration of probiotics and antibiotics, which can potentially...

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Bibliographic Details
Published in:Advanced materials (Weinheim) 2018-12, Vol.30 (51), p.n/a
Main Authors: Li, Zhihao, Behrens, Adam M., Ginat, Nitzan, Tzeng, Stephany Y., Lu, Xueguang, Sivan, Sarit, Langer, Robert, Jaklenec, Ana
Format: Article
Language:English
Subjects:
alginate
Alginates
Antibiotics
antimicrobial resistance
Biofilms
chronic wounds
Encapsulation
Materials science
Probiotics
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Summary:In article number 1803925, Robert Langer, Ana Jaklenec, and co‐workers demonstrate a biofilm‐inspired encapsulation of probiotics using alginate to confer temporary antibiotic protection to susceptible probiotics. This enables the coadministration of probiotics and antibiotics, which can potentially overcome antimicrobial resistance. The efficacy of this approach is demonstrated in vitro where two highly pathogenic bacteria found in chronic wounds are completely eradicated.
ISSN:0935-9648
1521-4095
DOI:10.1002/adma.201870389