Evaluation of ELISA and HBsAg Rapid Test Cassette Assay in Detection of Hepatitis B Virus

According to results presented in Table 2, the sensitivity and specificity were 100% for ELISA test compared to rapid test cassette assay. Discussion Hepatitis is one of the most important diseases and is a common cause a wide spectrum of liver diseases ranging from acute hepatitis to chronic hepati...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2018-12, Vol.10 (12), p.3157
Main Authors: Hussein, Areej Atiyah, Motib, Anfal Shakir, Hadi, Linda Munjed
Format: Article
Language:English
Subjects:
Age
Antigens
Blood & organ donations
Blood banks
Chromatography
Chronic illnesses
Deoxyribonucleic acid
DNA
Enzymes
Hepatitis
Hepatitis B
Immunoassay
Immunoglobulins
Infections
Liver cancer
Liver cirrhosis
Liver diseases
Onsite
Statistical analysis
Viral infections
Viruses
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Summary:According to results presented in Table 2, the sensitivity and specificity were 100% for ELISA test compared to rapid test cassette assay. Discussion Hepatitis is one of the most important diseases and is a common cause a wide spectrum of liver diseases ranging from acute hepatitis to chronic hepatitis, cirrhosis and liver cancer. [...]correct identification of the disease helps reduce its mortality and morbidity rates. Androgen and estrogen pathways were identified to play opposite regulations of HBV transcription by targeting viral enhancer I at molecular level. [...]in addition to the direct effects on HBV life cycle, sex hormones may also be involved in the immune response to hepatitis B virus infection and the progression of associated liver diseases though the detailed mechanisms are still unclear. [...]there is potentially substantial risk of hepatitis B virus transmission despite HBsAg testing and this is an important message for clinicians deciding to transfuse blood.
ISSN:0975-1459