Inbreeding depression in a Hereford beef cattle population using the pedigree and genomic information

Increase in inbreeding leads to loss in fitness and reduction in performance. Although its effects are clear, measuring inbreeding is often complicated by the lack of complete and error free pedigrees. Availability of high density marker panels provides an alternative tool to assess inbreeding. Addi...

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Bibliographic Details
Published in:Journal of animal science 2018-12, Vol.96, p.141-141
Main Authors: Sumreddee, P, Toghiani, S, Hay, E, Ling, A, Aggrey, S, Rekaya, R
Format: Article
Language:English
Subjects:
Animal populations
Animals
Birth weight
Breeding of animals
Cattle
Fertility
Fitness
Genomics
Homozygosity
Impact analysis
Inbreeding
Inbreeding depression
Marker panels
Pedigree
Population studies
Pregnancy
Progeny
Regression analysis
Single-nucleotide polymorphism
Weaning
Weight
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Summary:Increase in inbreeding leads to loss in fitness and reduction in performance. Although its effects are clear, measuring inbreeding is often complicated by the lack of complete and error free pedigrees. Availability of high density marker panels provides an alternative tool to assess inbreeding. Additionally, inbreeding depression seems to not only be affected by the animal level of inbreeding but also by its parent's inbreeding. The aim of this study was to determine the effects of the animal and its parent inbreeding on growth and fertility in a small Hereford population. Inbreeding was assessed based on pedigree (Fped), genomic relationship matrix (FGRM), and runs of homozygosity (FROH). The pedigree consisted of 10,476 animals spanning 48 generations. Genomic-based inbreeding was evaluated using 788 animals genotyped for 30,810 SNPs. Traits analyzed included growth (birth weight, weaning weight, yearling weight, and average daily gain) and fertility traits (age at first calving, and heifer pregnancy status). The phenotypic data consisted of records on 3,995 animals. Linear regression analyses were used to assess the effects of inbreeding. The percentage average inbreeding was 29.01 (SD=5.75), 14.80 (SD=10.53) and 22.91 (SD=5.14) for Fped, FGRM, and FROH, respectively. This high inbreeding was expected given the small size and the level of isolation of the used population. An increase of 1% in animal inbreeding resulted in a decrease of 1.07 and 1.10 kg in yearling weight for Fped and FROH, respectively. Similarly, ADG was reduced by 0.002 to 0.01 kg. Inbreeding increased significantly the age at first calving but not the pregnancy status. Joint estimates of animal and sire's (FS) or dam's (FD) inbreeding effects showed a clear effect of FD on the progeny performance. The sire inbreeding has limited effects. The high inbreeding level of the studied population seems to have impacted both production and fertility traits.
ISSN:0021-8812
1525-3163