Transfection of the CD20 cell surface molecule into ectopic cell types generates a Ca(2plus) conductance found constitutively in B lymphocytes

The hypothesis that CD20 mediates a plasma membrane ionic conductance in B lymphocytes was examined. The findings demonstrate that CD20 plays a direct role in the regulation of transmembrane conductive Ca2plus flux.

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Bibliographic Details
Published in:The Journal of cell biology 1993-06, Vol.121 (5), p.1121
Main Authors: Bubien, James K, Zhou, Liang-Ji, Bell, P Darwin, Frizzell, Raymond A, Tedder, Thomas F
Format: Article
Language:English
Subjects:
Cellular biology
Online Access:Get full text
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Description
Summary:The hypothesis that CD20 mediates a plasma membrane ionic conductance in B lymphocytes was examined. The findings demonstrate that CD20 plays a direct role in the regulation of transmembrane conductive Ca2plus flux.
ISSN:0021-9525
1540-8140
DOI:10.1083/jcb.121.5.1121