Loading…

Case of chronic lymphocytic leukemia with unusual chromosome aberrations

Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identif...

Full description

Saved in:
Bibliographic Details
Published in:International journal of hematology 2004-11, Vol.80 (4), p.351-353
Main Authors: HSIAO, Hui-Hua, HUNG, Yi-Hui, HSIAO, Hui-Pin, TSENG, Shih-Bin, TSAI, Hui-Jen, LIU, Yi-Chang, LIU, Ta-Chih, CHAO, Mei-Chyn, YULI CHANG, LIN, Sheng-Fung
Format: Article
Language:English
Subjects:
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
cited_by cdi_FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3
cites cdi_FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3
container_end_page 353
container_issue 4
container_start_page 351
container_title International journal of hematology
container_volume 80
creator HSIAO, Hui-Hua
HUNG, Yi-Hui
HSIAO, Hui-Pin
TSENG, Shih-Bin
TSAI, Hui-Jen
LIU, Yi-Chang
LIU, Ta-Chih
CHAO, Mei-Chyn
YULI CHANG
LIN, Sheng-Fung
description Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identified by chromosome banding analysis and confirmed by fluorescence in situ hybridization analysis of interphase cells. Because of the rarity of these changes, possible molecular mechanisms associated with this karyotype are discussed.
doi_str_mv 10.1532/IJH97.A10323
format article
fullrecord <record><control><sourceid>proquest_cross</sourceid><recordid>TN_cdi_proquest_journals_217393128</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>1879947791</sourcerecordid><originalsourceid>FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3</originalsourceid><addsrcrecordid>eNpF0EFLwzAUwPEgipvTm2cpgjc78_KapD2OoW4y8KLnkqYJ61ybmbTIvr3dVtjpvcOP9-BPyD3QKXBkL8uPRSanM6DI8IKMIRU8RimTSzKmGeMxl0BH5CaEDaUgaSKvyQi4AM4EHZPFXAUTORvptXdNpaPtvt6tnd63h910P6auVPRXteuoa7rQqe1R1i642kSqMN6rtnJNuCVXVm2DuRvmhHy_vX7NF_Hq8305n61ijUK0sRECJGRYoOapLKVEqzjPUFoBqEo0qZFFgsoYZgEyy9ICZUmTggqT2MTihDye7u68--1MaPON63zTv8wZSMwQWNqj5xPS3oXgjc13vqqV3-dA80O1_FgtP1Xr-cNwsytqU57xkKkHTwNQQaut9arRVTg7gUz0Fv8B9ud0KA</addsrcrecordid><sourcetype>Aggregation Database</sourcetype><iscdi>true</iscdi><recordtype>article</recordtype><pqid>217393128</pqid></control><display><type>article</type><title>Case of chronic lymphocytic leukemia with unusual chromosome aberrations</title><source>Springer Nature</source><creator>HSIAO, Hui-Hua ; HUNG, Yi-Hui ; HSIAO, Hui-Pin ; TSENG, Shih-Bin ; TSAI, Hui-Jen ; LIU, Yi-Chang ; LIU, Ta-Chih ; CHAO, Mei-Chyn ; YULI CHANG ; LIN, Sheng-Fung</creator><creatorcontrib>HSIAO, Hui-Hua ; HUNG, Yi-Hui ; HSIAO, Hui-Pin ; TSENG, Shih-Bin ; TSAI, Hui-Jen ; LIU, Yi-Chang ; LIU, Ta-Chih ; CHAO, Mei-Chyn ; YULI CHANG ; LIN, Sheng-Fung</creatorcontrib><description>Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identified by chromosome banding analysis and confirmed by fluorescence in situ hybridization analysis of interphase cells. Because of the rarity of these changes, possible molecular mechanisms associated with this karyotype are discussed.</description><identifier>ISSN: 0925-5710</identifier><identifier>EISSN: 1865-3774</identifier><identifier>DOI: 10.1532/IJH97.A10323</identifier><identifier>PMID: 15615260</identifier><language>eng</language><publisher>Tokyo: Springer</publisher><subject>Aged ; Biological and medical sciences ; Chromosomes, Human, Pair 22 ; Chromosomes, Human, Pair 6 ; Chromosomes, Human, Pair 8 ; Fatal Outcome ; Hematologic and hematopoietic diseases ; Humans ; Leukemia, Lymphocytic, Chronic, B-Cell - genetics ; Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis ; Male ; Medical sciences ; Translocation, Genetic</subject><ispartof>International journal of hematology, 2004-11, Vol.80 (4), p.351-353</ispartof><rights>2005 INIST-CNRS</rights><rights>The Japanese Society of Hematology 2004</rights><lds50>peer_reviewed</lds50><woscitedreferencessubscribed>false</woscitedreferencessubscribed><citedby>FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3</citedby><cites>FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3</cites></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><link.rule.ids>314,780,784,27924,27925</link.rule.ids><backlink>$$Uhttp://pascal-francis.inist.fr/vibad/index.php?action=getRecordDetail&amp;idt=16326561$$DView record in Pascal Francis$$Hfree_for_read</backlink><backlink>$$Uhttps://www.ncbi.nlm.nih.gov/pubmed/15615260$$D View this record in MEDLINE/PubMed$$Hfree_for_read</backlink></links><search><creatorcontrib>HSIAO, Hui-Hua</creatorcontrib><creatorcontrib>HUNG, Yi-Hui</creatorcontrib><creatorcontrib>HSIAO, Hui-Pin</creatorcontrib><creatorcontrib>TSENG, Shih-Bin</creatorcontrib><creatorcontrib>TSAI, Hui-Jen</creatorcontrib><creatorcontrib>LIU, Yi-Chang</creatorcontrib><creatorcontrib>LIU, Ta-Chih</creatorcontrib><creatorcontrib>CHAO, Mei-Chyn</creatorcontrib><creatorcontrib>YULI CHANG</creatorcontrib><creatorcontrib>LIN, Sheng-Fung</creatorcontrib><title>Case of chronic lymphocytic leukemia with unusual chromosome aberrations</title><title>International journal of hematology</title><addtitle>Int J Hematol</addtitle><description>Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identified by chromosome banding analysis and confirmed by fluorescence in situ hybridization analysis of interphase cells. Because of the rarity of these changes, possible molecular mechanisms associated with this karyotype are discussed.</description><subject>Aged</subject><subject>Biological and medical sciences</subject><subject>Chromosomes, Human, Pair 22</subject><subject>Chromosomes, Human, Pair 6</subject><subject>Chromosomes, Human, Pair 8</subject><subject>Fatal Outcome</subject><subject>Hematologic and hematopoietic diseases</subject><subject>Humans</subject><subject>Leukemia, Lymphocytic, Chronic, B-Cell - genetics</subject><subject>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</subject><subject>Male</subject><subject>Medical sciences</subject><subject>Translocation, Genetic</subject><issn>0925-5710</issn><issn>1865-3774</issn><fulltext>true</fulltext><rsrctype>article</rsrctype><creationdate>2004</creationdate><recordtype>article</recordtype><recordid>eNpF0EFLwzAUwPEgipvTm2cpgjc78_KapD2OoW4y8KLnkqYJ61ybmbTIvr3dVtjpvcOP9-BPyD3QKXBkL8uPRSanM6DI8IKMIRU8RimTSzKmGeMxl0BH5CaEDaUgaSKvyQi4AM4EHZPFXAUTORvptXdNpaPtvt6tnd63h910P6auVPRXteuoa7rQqe1R1i642kSqMN6rtnJNuCVXVm2DuRvmhHy_vX7NF_Hq8305n61ijUK0sRECJGRYoOapLKVEqzjPUFoBqEo0qZFFgsoYZgEyy9ICZUmTggqT2MTihDye7u68--1MaPON63zTv8wZSMwQWNqj5xPS3oXgjc13vqqV3-dA80O1_FgtP1Xr-cNwsytqU57xkKkHTwNQQaut9arRVTg7gUz0Fv8B9ud0KA</recordid><startdate>20041101</startdate><enddate>20041101</enddate><creator>HSIAO, Hui-Hua</creator><creator>HUNG, Yi-Hui</creator><creator>HSIAO, Hui-Pin</creator><creator>TSENG, Shih-Bin</creator><creator>TSAI, Hui-Jen</creator><creator>LIU, Yi-Chang</creator><creator>LIU, Ta-Chih</creator><creator>CHAO, Mei-Chyn</creator><creator>YULI CHANG</creator><creator>LIN, Sheng-Fung</creator><general>Springer</general><general>Springer Nature B.V</general><scope>IQODW</scope><scope>CGR</scope><scope>CUY</scope><scope>CVF</scope><scope>ECM</scope><scope>EIF</scope><scope>NPM</scope><scope>AAYXX</scope><scope>CITATION</scope><scope>3V.</scope><scope>7RV</scope><scope>7T5</scope><scope>7T7</scope><scope>7TM</scope><scope>7X7</scope><scope>7XB</scope><scope>88E</scope><scope>8AO</scope><scope>8FD</scope><scope>8FI</scope><scope>8FJ</scope><scope>8FK</scope><scope>ABUWG</scope><scope>AFKRA</scope><scope>BENPR</scope><scope>C1K</scope><scope>CCPQU</scope><scope>FR3</scope><scope>FYUFA</scope><scope>GHDGH</scope><scope>H94</scope><scope>K9.</scope><scope>KB0</scope><scope>M0S</scope><scope>M1P</scope><scope>NAPCQ</scope><scope>P64</scope><scope>PQEST</scope><scope>PQQKQ</scope><scope>PQUKI</scope></search><sort><creationdate>20041101</creationdate><title>Case of chronic lymphocytic leukemia with unusual chromosome aberrations</title><author>HSIAO, Hui-Hua ; HUNG, Yi-Hui ; HSIAO, Hui-Pin ; TSENG, Shih-Bin ; TSAI, Hui-Jen ; LIU, Yi-Chang ; LIU, Ta-Chih ; CHAO, Mei-Chyn ; YULI CHANG ; LIN, Sheng-Fung</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3</frbrgroupid><rsrctype>articles</rsrctype><prefilter>articles</prefilter><language>eng</language><creationdate>2004</creationdate><topic>Aged</topic><topic>Biological and medical sciences</topic><topic>Chromosomes, Human, Pair 22</topic><topic>Chromosomes, Human, Pair 6</topic><topic>Chromosomes, Human, Pair 8</topic><topic>Fatal Outcome</topic><topic>Hematologic and hematopoietic diseases</topic><topic>Humans</topic><topic>Leukemia, Lymphocytic, Chronic, B-Cell - genetics</topic><topic>Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis</topic><topic>Male</topic><topic>Medical sciences</topic><topic>Translocation, Genetic</topic><toplevel>peer_reviewed</toplevel><toplevel>online_resources</toplevel><creatorcontrib>HSIAO, Hui-Hua</creatorcontrib><creatorcontrib>HUNG, Yi-Hui</creatorcontrib><creatorcontrib>HSIAO, Hui-Pin</creatorcontrib><creatorcontrib>TSENG, Shih-Bin</creatorcontrib><creatorcontrib>TSAI, Hui-Jen</creatorcontrib><creatorcontrib>LIU, Yi-Chang</creatorcontrib><creatorcontrib>LIU, Ta-Chih</creatorcontrib><creatorcontrib>CHAO, Mei-Chyn</creatorcontrib><creatorcontrib>YULI CHANG</creatorcontrib><creatorcontrib>LIN, Sheng-Fung</creatorcontrib><collection>Pascal-Francis</collection><collection>Medline</collection><collection>MEDLINE</collection><collection>MEDLINE (Ovid)</collection><collection>MEDLINE</collection><collection>MEDLINE</collection><collection>PubMed</collection><collection>CrossRef</collection><collection>ProQuest Central (Corporate)</collection><collection>Nursing &amp; Allied Health Database</collection><collection>Immunology Abstracts</collection><collection>Industrial and Applied Microbiology Abstracts (Microbiology A)</collection><collection>Nucleic Acids Abstracts</collection><collection>ProQuest Health &amp; Medical Collection</collection><collection>ProQuest Central (purchase pre-March 2016)</collection><collection>Medical Database (Alumni Edition)</collection><collection>ProQuest Pharma Collection</collection><collection>Technology Research Database</collection><collection>Hospital Premium Collection</collection><collection>Hospital Premium Collection (Alumni Edition)</collection><collection>ProQuest Central (Alumni) (purchase pre-March 2016)</collection><collection>ProQuest Central (Alumni)</collection><collection>ProQuest Central</collection><collection>AUTh Library subscriptions: ProQuest Central</collection><collection>Environmental Sciences and Pollution Management</collection><collection>ProQuest One Community College</collection><collection>Engineering Research Database</collection><collection>Health Research Premium Collection</collection><collection>Health Research Premium Collection (Alumni)</collection><collection>AIDS and Cancer Research Abstracts</collection><collection>ProQuest Health &amp; Medical Complete (Alumni)</collection><collection>Nursing &amp; Allied Health Database (Alumni Edition)</collection><collection>Health &amp; Medical Collection (Alumni Edition)</collection><collection>Medical Database</collection><collection>Nursing &amp; Allied Health Premium</collection><collection>Biotechnology and BioEngineering Abstracts</collection><collection>ProQuest One Academic Eastern Edition (DO NOT USE)</collection><collection>ProQuest One Academic</collection><collection>ProQuest One Academic UKI Edition</collection><jtitle>International journal of hematology</jtitle></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext</fulltext></delivery><addata><au>HSIAO, Hui-Hua</au><au>HUNG, Yi-Hui</au><au>HSIAO, Hui-Pin</au><au>TSENG, Shih-Bin</au><au>TSAI, Hui-Jen</au><au>LIU, Yi-Chang</au><au>LIU, Ta-Chih</au><au>CHAO, Mei-Chyn</au><au>YULI CHANG</au><au>LIN, Sheng-Fung</au><format>journal</format><genre>article</genre><ristype>JOUR</ristype><atitle>Case of chronic lymphocytic leukemia with unusual chromosome aberrations</atitle><jtitle>International journal of hematology</jtitle><addtitle>Int J Hematol</addtitle><date>2004-11-01</date><risdate>2004</risdate><volume>80</volume><issue>4</issue><spage>351</spage><epage>353</epage><pages>351-353</pages><issn>0925-5710</issn><eissn>1865-3774</eissn><abstract>Chronic lymphocytic leukemia is one of the most common leukemias in the western world and consists of many chromosome aberrations. We report the case of a 74-year-old male patient with chronic lymphocytic leukemia with complex variant translocations t(8;22)(q24;q11) and der(8)t(6;8)(p21;p21) identified by chromosome banding analysis and confirmed by fluorescence in situ hybridization analysis of interphase cells. Because of the rarity of these changes, possible molecular mechanisms associated with this karyotype are discussed.</abstract><cop>Tokyo</cop><pub>Springer</pub><pmid>15615260</pmid><doi>10.1532/IJH97.A10323</doi><tpages>3</tpages></addata></record>
fulltext fulltext
identifier ISSN: 0925-5710
ispartof International journal of hematology, 2004-11, Vol.80 (4), p.351-353
issn 0925-5710
1865-3774
language eng
recordid cdi_proquest_journals_217393128
source Springer Nature
subjects Aged
Biological and medical sciences
Chromosomes, Human, Pair 22
Chromosomes, Human, Pair 6
Chromosomes, Human, Pair 8
Fatal Outcome
Hematologic and hematopoietic diseases
Humans
Leukemia, Lymphocytic, Chronic, B-Cell - genetics
Leukemias. Malignant lymphomas. Malignant reticulosis. Myelofibrosis
Male
Medical sciences
Translocation, Genetic
title Case of chronic lymphocytic leukemia with unusual chromosome aberrations
url http://sfxeu10.hosted.exlibrisgroup.com/loughborough?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-25T18%3A01%3A34IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-proquest_cross&rft_val_fmt=info:ofi/fmt:kev:mtx:journal&rft.genre=article&rft.atitle=Case%20of%20chronic%20lymphocytic%20leukemia%20with%20unusual%20chromosome%20aberrations&rft.jtitle=International%20journal%20of%20hematology&rft.au=HSIAO,%20Hui-Hua&rft.date=2004-11-01&rft.volume=80&rft.issue=4&rft.spage=351&rft.epage=353&rft.pages=351-353&rft.issn=0925-5710&rft.eissn=1865-3774&rft_id=info:doi/10.1532/IJH97.A10323&rft_dat=%3Cproquest_cross%3E1879947791%3C/proquest_cross%3E%3Cgrp_id%3Ecdi_FETCH-LOGICAL-c366t-e6617193b3c587d773fa55937f613ad3e8e7b43aee2f119f28b37d04b06e4f4f3%3C/grp_id%3E%3Coa%3E%3C/oa%3E%3Curl%3E%3C/url%3E&rft_id=info:oai/&rft_pqid=217393128&rft_id=info:pmid/15615260&rfr_iscdi=true