Rapid and sensitive electrochemical detection of myricetin based on polyoxometalates/SnO2/gold nanoparticles ternary nanocomposite film electrode

• Published in: Sensors and actuators. B, Chemical Chemical, 2019-03, Vol.283, p.35-41
• Main Authors: Xing, Ruimin, Tong, Liangyu, Zhao, Xiaoyu, Liu, Hongling, Ma, Pengtao, Zhao, Junwei, Liu, Xiaoqiang, Liu, Shanhu
• Format: Article
• Language: English
• Subjects: Economic conditions; Electrochemical; Electrochemical analysis; Electrodes; Gold; Myricetin; Nanocomposites; Nanoparticles; Nanospheres; Oxidation; Polyoxometalates; Polyoxometallates; Reproducibility; Response time; Self-assembly; Sensor; Tin dioxide
• ISSN: 0925-4005; 1873-3077
• DOI: 10.1016/j.snb.2018.11.129

Electrochemical detection of myricetin is rapid and economic but has been rarely reported so far. A layer-by-layer self-assembly strategy was developed to fabricate a ternary nanocomposite film containing P2W18 clusters, mesoporous SnO2 nanospheres and AuNPs on the ITO electrode for the electrochemical determination of myricetin. Compared with all the other electrodes herein and previously reported, the (P2W18-SnO2-AuNPs)3/ITO widened the determination range of myricetin from 1 to 110 μmol/L with quick response time. [Display omitted] •A ternary nanocomposite film electrode based on P2W18/SnO2/AuNPs was fabricated.•The (P2W18-SnO2-AuNPs)3/ITO exhibits extraordinary electrocatalytic activity towards myricetin.•Rapid and sensitive electrochemical detection of myricetin with a wider linear range was achieved.•Superior stability and reproducibility suggested the practical applicability of the prepared sensor. Electrochemical detection of myricetin is rapid and economic but has been rarely reported so far. Here we present a layer-by-layer self-assembly strategy to fabricate a ternary nanocomposite film containing polyoxometalate P2W18 clusters, mesoporous SnO2 nanospheres and Au nanoparticles (AuNPs) on the ITO electrode for the electrochemical determination of myricetin. Compared with all the other electrodes herein and previously reported, the (P2W18-SnO2-AuNPs)3/ITO widened the electrochemical determination range of myricetin from 1 to 110 μmol/L with quick response time, which was extended for the myricetin detection in juice samples with satisfactory recoveries between 97.65% and 103.07%. The extraordinary electrocatalytic activity could be attributed to the synergetic contribution of three components, namely P2W18 with multi-electron reversible electrocatalytic properties, mesoporous SnO2 nanospheres with high conductivity and electroactive surface area, and AuNPs with outstanding conductivity and electrocatalytic properties. With superior stability, reproducibility and anti-interferences against common coexisting ions, the presented method would cater for the requirements of clinics and pharmaceuticals for the rapid and sensitive determination of myricetin in real samples.