High genetic diversity of noroviruses in children from a community-based study in Rio de Janeiro, Brazil, 2014-2018

We report on the occurrence and diversity of noroviruses in children (younger than 5 years old of age) from a low-income urban area in Rio de Janeiro, Brazil. Sixty-one stool specimens collected from children between 1 and 4 years old with acute diarrhoeic episodes (ADE) and non-ADE were investigate...

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Bibliographic Details
Published in:Archives of virology 2019-05, Vol.164 (5), p.1427-1432
Main Authors: Cantelli, Carina Pacheco, da Silva, Marcelle Figueira Marques, Fumian, Tulio Machado, da Cunha, Denise Cotrim, Andrade, Juliana da Silva Ribeiro de, Malta, Fábio Correia, da Silva e Mouta Junior, Sérgio, Fialho, Alexandre Madi, de Moraes, Marcia Terezinha Baroni, Brasil, Patricia, Miagostovich, Marize Pereira, Leite, José Paulo Gagliardi
Format: Article
Language:English
Subjects:
Biomedical and Life Sciences
Biomedicine
Brief Report
Children
Genetic diversity
Genotypes
Infectious Diseases
Medical Microbiology
Polymerase chain reaction
Virology
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Summary:We report on the occurrence and diversity of noroviruses in children (younger than 5 years old of age) from a low-income urban area in Rio de Janeiro, Brazil. Sixty-one stool specimens collected from children between 1 and 4 years old with acute diarrhoeic episodes (ADE) and non-ADE were investigated. RT-qPCR and sequencing of PCR products after conventional RT-PCR analysis were performed. Noroviruses were detected in 29 (47.5%) samples: 21 (46.7%) from cases with ADE and 8 (50%) from non-ADE cases. Molecular characterization showed 10 different genotypes circulating in this community between November 2014 and April 2018.
ISSN:0304-8608
1432-8798
DOI:10.1007/s00705-019-04195-z