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Quinoline-Thioureidopeptides: A New Approach for the Synthesis of Quinoline-Isothiocyanate and Their Peptide Linkage

We present an efficient synthetic route for quinoline condensed thioureidopeptidyl esters from corresponding isothiocyanate and amino acid esters. The utility of quinoline isothiocyanate as major building block for desired thioureidopeptides of quinoline interests, with good yield with excellent pur...

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Bibliographic Details
Published in:International journal of peptide research and therapeutics 2009-09, Vol.15 (3), p.233-239
Main Authors: Aravinda, T., Bhojya Naik, H. S., Prakash Naik, H. R., Suresh babu, V. V., Hemantha, H. P.
Format: Article
Language:English
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Summary:We present an efficient synthetic route for quinoline condensed thioureidopeptidyl esters from corresponding isothiocyanate and amino acid esters. The utility of quinoline isothiocyanate as major building block for desired thioureidopeptides of quinoline interests, with good yield with excellent purity. All the new compounds are well characterized by IR, 1 H NMR, mass and elemental analysis data.
ISSN:1573-3149
1573-3904
DOI:10.1007/s10989-009-9184-1