Chitosan supplementation does not affect fat absorption in healthy males fed a high-fat diet, a pilot study

BACKGROUND:: The use of dietary supplements, especially those for weight control, is increasing. Advertising claims for some of these supplements may give consumers unrealistic expectations. For example, it is claimed that the supplement chitosan can block the absorption of up to 120 g of dietary fa...

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Bibliographic Details
Published in:International Journal of Obesity 2002-01, Vol.26 (1), p.119-122
Main Authors: GADESL, M. D, STERN, J. S
Format: Article
Language:English
Subjects:
Absorption
Biological and medical sciences
Body mass index
Charcoal
Dietary supplements
Feces
Feeding. Feeding behavior
Food
Fundamental and applied biological sciences. Psychology
Males
Medical sciences
Miscellaneous
Nutrition research
Oils & fats
Radiotherapy. Instrumental treatment. Physiotherapy. Reeducation. Rehabilitation, orthophony, crenotherapy. Diet therapy and various other treatments (general aspects)
Vertebrates: anatomy and physiology, studies on body, several organs or systems
Weight control
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Summary:BACKGROUND:: The use of dietary supplements, especially those for weight control, is increasing. Advertising claims for some of these supplements may give consumers unrealistic expectations. For example, it is claimed that the supplement chitosan can block the absorption of up to 120 g of dietary fat per day. OBJECTIVE:: To test the effect of a chitosan supplement used as directed, on the absorption of dietary fat. DESIGN:: Seven healthy male volunteers with average age 28, range 23-30, average body mass index (BMI) 26, range 23-31, maintained a high fat intake (>120 g/day) for 12 days. On days 6-9, chitosan was taken as directed by the manufacturer prior to meals and snacks and totaled 15 capsules or 5.25 g of chitosan daily. A charcoal marker was consumed on days 2, 6 and 10 to mark the baseline and supplement periods. All feces were collected on days 2-12, and were divided based on the appearance of charcoal in the feces. Fecal fat content corresponding to the four baseline and four chitosan-supplemented days was measured. RESULTS:: Average dietary fat intake did not differ between baseline (135±5 g), and chitosan (135±3 g) periods. Fecal fat excretion did not differ between the two periods (6.9±1.0 g/day baseline; 6.8±0.4 g/day chitosan). The fecal fat content as a percentage of fat consumed did not differ (5.1±0.7% baseline, 5.0±0.3% chitosan). Fecal mass did not differ (176±26 g/day baseline, 182±14 g/day chitosan). CONCLUSION:: Consumption of this chitosan supplement did not increase fecal fat content and therefore did not block fat absorption. INTERNATIONAL JOURNAL OF OBESITY: (2002) 26, 119-122. DOI: 10.1038/sj.ijo.0801859
ISSN:0307-0565
1476-5497
DOI:10.1038/sj.ijo.0801859