Fixed Bin Frequency Distributions for the VNTR Locus D5S110 in General United States Reference Databases

Fixed bin frequencies for the D5S110 locus were determined in African Americans, Caucasians, Southeastern Hispanics, and Southwestern Hispanics. The data were generated by RFLP analysis of HAE III-digested genomic DNA. The D5S110 locus met Hardy-Weinberg expectations in the four sample populations,...

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Bibliographic Details
Published in:Journal of forensic sciences 1995-03, Vol.40 (2), p.236-238
Main Authors: Budowle, B, Giusti, AM
Format: Article
Language:English
Subjects:
Black or African American
Black People - genetics
Chromosome Mapping
Confidence Intervals
DNA - analysis
Gene Frequency
Genetics, Population
Hispanic or Latino - genetics
Humans
Information Systems
Likelihood Functions
Minisatellite Repeats
Polymorphism, Restriction Fragment Length
United States
White People - genetics
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Summary:Fixed bin frequencies for the D5S110 locus were determined in African Americans, Caucasians, Southeastern Hispanics, and Southwestern Hispanics. The data were generated by RFLP analysis of HAE III-digested genomic DNA. The D5S110 locus met Hardy-Weinberg expectations in the four sample populations, and there is no evidence for association of alleles between the D5S110 and other routinely used VNTR loci. The frequency data can be used in forensic analyses and paternity tests to estimate the frequency of a DNA profile in various general United States populations.
ISSN:0022-1198
1556-4029
DOI:10.1520/JFS15348J