Greek Cypriot Allele and Genotype Frequencies for Amplitype® PM-DQA1 and D1S80 Loci

A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequ...

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Bibliographic Details
Published in:Journal of forensic sciences 1998-05, Vol.43 (3), p.661-664
Main Authors: Cariolou, MA, Manoli, P, Christophorou, M, Bashiardes, E, Karagrigoriou, A, Budowle, B
Format: Article
Language:English
Subjects:
Alleles
Cyprus
DNA Fingerprinting - methods
Ethnic Groups - genetics
Gene Frequency
Genetic Heterogeneity
Genetic Markers - genetics
Genotype
Greece - ethnology
Histocompatibility Testing
HLA-DQ alpha-Chains
HLA-DQ Antigens - genetics
Humans
Polymerase Chain Reaction
Reagent Kits, Diagnostic
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Summary:A sample from the Greek Cypriot population was typed at seven forensically important PCR-based loci: LDLR, GYPA, HBGG, D7S8, GC, HLA-DQA1, and D1S80. The results showed that all loci meet Hardy-Weinberg expectations and that there is no evidence for association of alleles between loci. Allelic frequency distributions at all loci, except HLA-DQA1 and two D1S80 alleles, were similar to those of U.S. Caucasians. Greek Cypriot population databases have been created and can be used for forensic analyses to estimate the frequency of a multiple locus DNA profile.
ISSN:0022-1198
1556-4029
DOI:10.1520/JFS16199J