Current Concepts in the Diagnosis and Management of Metabolic Complications of HIV Infection and Its Therapy

Changes in fat distribution, dyslipidemia, disordered glucose metabolism, and lactic acidosis have emerged as significant challenges to the treatment of human immunodeficiency virus (HIV) infection. Over the past decade, numerous investigations have been conducted to better define these conditions,...

Full description

Saved in:
Bibliographic Details
Published in:Clinical infectious diseases 2006-09, Vol.43 (5), p.645-653
Main Authors: Wohl, D. A., McComsey, G., Tebas, P., Brown, T. T., Glesby, M. J., Reeds, D., Shikuma, C., Mulligan, K., Dube, M., Wininger, D., Huang, J., Revuelta, M., Currier, J., Swindells, S., Fichtenbaum, C., Basar, M., Tungsiripat, M., Meyer, W., Weihe, J., Wanke, C.
Format: Article
Language:English
Subjects:
Adipose tissues
AIDS
Antiretrovirals
Biological and medical sciences
Body fat
Dyslipidemias - diagnosis
Dyslipidemias - etiology
Dyslipidemias - therapy
Glucose Metabolism Disorders - etiology
Glucose Metabolism Disorders - therapy
HIV
HIV infections
HIV Infections - complications
HIV-Associated Lipodystrophy Syndrome - chemically induced
HIV-Associated Lipodystrophy Syndrome - diagnosis
HIV-Associated Lipodystrophy Syndrome - therapy
HIV/AIDS
Human immunodeficiency virus
Human viral diseases
Humans
Immunodeficiencies
Immunodeficiencies. Immunoglobulinopathies
Immunopathology
Infectious diseases
Insulin resistance
Lipids
Medical diagnosis
Medical sciences
Medical treatment
Metabolic disorders
Predisposing factors
Subcutaneous fat
Viral diseases
Viral diseases of the lymphoid tissue and the blood. Aids
Citations: Items that this one cites
Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:Changes in fat distribution, dyslipidemia, disordered glucose metabolism, and lactic acidosis have emerged as significant challenges to the treatment of human immunodeficiency virus (HIV) infection. Over the past decade, numerous investigations have been conducted to better define these conditions, identify risk factors associated with their development, and test potential therapeutic interventions. The lack of standardized diagnostic criteria, as well as disparate study populations and research methods, have led to conflicting data regarding the diagnosis and treatment of metabolic and body shape disorders associated with HIV infection. On the basis of a review of the medical literature published and/or data presented before April 2006, we have prepared a guide to assist the clinician in the detection and management of these complications.
ISSN:1058-4838
1537-6591
DOI:10.1086/507333