One-pot facile synthesis of novel 1,2,3-triazole-appended α-aminophosphonates

New α-aminophosphonates bearing 1,2,3-triazolyl moiety were easily synthesized by one-pot reaction of 1-aryl- 1H -1,2,3-triazole-4-carbaldehydes, anilines and trimethyl phosphite in good to excellent yields. All the synthesized compounds were characterized by IR, 1 H NMR and 13 C NMR analysis. These...

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Bibliographic Details
Published in:Journal of the Iranian Chemical Society 2019-05, Vol.16 (5), p.953-961
Main Authors: Danne, Ashruba B., Akolkar, Satish V., Deshmukh, Tejshri R., Siddiqui, Madiha M., Shingate, Bapurao B.
Format: Article
Language:English
Subjects:
Analytical Chemistry
Aromatic compounds
Biochemistry
Chemical synthesis
Chemistry
Chemistry and Materials Science
Inorganic Chemistry
NMR
Nuclear magnetic resonance
Organic Chemistry
Original Paper
Physical Chemistry
Triazoles
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Summary:New α-aminophosphonates bearing 1,2,3-triazolyl moiety were easily synthesized by one-pot reaction of 1-aryl- 1H -1,2,3-triazole-4-carbaldehydes, anilines and trimethyl phosphite in good to excellent yields. All the synthesized compounds were characterized by IR, 1 H NMR and 13 C NMR analysis. These novel 1,2,3-triazole-incorporated α-aminophosphonates may be potential biological compounds due to the presence of both important moieties, 1,2,3-triazole and aminophosphonates. Graphical abstract
ISSN:1735-207X
1735-2428
DOI:10.1007/s13738-018-1571-0