Clinical aspects of substance review in persons with schizophrenia

To review the current knowledge on the problem of psychoactive substance abuse by persons with schizophrenia, with particular attention to issues of direct relevance to clinical practice. The author examined the literature from the last 2 decades and data from studies in which he was involved. Schiz...

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Bibliographic Details
Published in:Canadian journal of psychiatry 2003-02, Vol.48 (1), p.14
Main Author: Negrete, Juan C
Format: Article
Language:English
Subjects:
Drug abuse
Patients
Schizophrenia
Online Access:Get full text
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Summary:To review the current knowledge on the problem of psychoactive substance abuse by persons with schizophrenia, with particular attention to issues of direct relevance to clinical practice. The author examined the literature from the last 2 decades and data from studies in which he was involved. Schizophrenia sufferers show an elevated liability for substance abuse. Such comorbidity may derive from self-medication attempts, a common neuropathology for addiction and schizophrenia, the psychotogenic properties of certain drugs, or the influence of environmental factors. Among schizophrenia patients receiving treatment, substance misuse is associated with more severe symptoms and poorer therapeutic response. The presence of a chronic psychosis impedes treatment of the substance problem in traditional, nonpsychiatric addiction programs. Better outcomes are observed in integrated therapy services, where patients receive appropriate care for both conditions. Dual-pathology patients need comprehensive care with appropriate pharmacotherapy and psychosocial interventions. This treatment can be best provided within the context of a continuing care psychiatric service.
ISSN:0706-7437
1497-0015