New study suggests patients with advanced prostate cancer on androgen deprivation therapy need more dialogue with health care provider, especially around cardiovascular risk

• Published in: World journal of urology 2019-06, Vol.37 (6), p.1085-1093
• Main Authors: Merseburger, Axel, Bro Falkenberg, Anne, Kornilova, Olga J.
• Format: Article
• Language: English
• Subjects: Aged; Aged, 80 and over; Androgen Antagonists - adverse effects; Androgen Antagonists - therapeutic use; Cardiovascular diseases; Cardiovascular Diseases - epidemiology; Cardiovascular Diseases - etiology; Communication; Health Knowledge, Attitudes, Practice; Health Personnel; Humans; Male; Medicine; Medicine & Public Health; Middle Aged; Neoplasm Staging; Nephrology; Oncology; Original Article; Patient Education as Topic; Patients; Physician-Patient Relations; Prostate cancer; Prostatic Neoplasms - complications; Prostatic Neoplasms - drug therapy; Prostatic Neoplasms - pathology; Risk Factors; Urology; Well being
• ISSN: 0724-4983; 1433-8726
• DOI: 10.1007/s00345-018-2495-0

Purpose To study the current level of patients’ awareness, and patient-health care provider (HCP) dialogue with respect to treatment-related risks, especially cardiovascular risk (CVR) associated with advanced prostate cancer (PCa) treatment. Methods This 10-min online survey summarised data by treatment, region, and CVR (high or low). Results Of the 411 patients, 83% were at high CVR while only 8% patients were aware of CVR associated with PCa treatment, majority of which (80%) were informed about this risk by HCPs. No significant difference in treatment approach was reported, regardless of patient’s CVR status. Compared to other potential risks, patients were more likely to initiate discussion about heart problems with HCPs (38% patients). When prompted, 26% patients rated heart problems as the most concerning risk factor, and this concern was twice in patients with high CVR (28%) versus low CVR (14%). Lifestyle modifications were made by 64% patients, of which 45% patients reported an improvement in overall well-being. Improved diet was the most adopted lifestyle modification. Conclusion There is a need to enhance a constant patient–HCP dialogue, and both groups need to make a conscious effort in that direction. This would help in increasing patients’ awareness of risks, having better treatment choice and acceptance, and reducing side-effects.