Loading…
A new facile method for the synthesis of 3-imidazolylpropionic acid N-oxides
A facile and efficient method for the preparation of 3-imidazolylpropionic acid N -oxides has been developed. It involves condensation of 2-unsubstituted imidazole N -oxide with an aldehyde and Meldrum's acid followed by hydrolysis and decarboxylation of the corresponding adduct. This method to...
Saved in:
Published in: | Chemistry of heterocyclic compounds (New York, N.Y. 1965) N.Y. 1965), 2019-02, Vol.55 (2), p.147-155 |
---|---|
Main Authors: | , , , , , , , |
Format: | Article |
Language: | English |
Subjects: | |
Citations: | Items that this one cites Items that cite this one |
Online Access: | Get full text |
Tags: |
Add Tag
No Tags, Be the first to tag this record!
|
Summary: | A facile and efficient method for the preparation of 3-imidazolylpropionic acid
N
-oxides has been developed. It involves condensation of 2-unsubstituted imidazole
N
-oxide with an aldehyde and Meldrum's acid followed by hydrolysis and decarboxylation of the corresponding adduct. This method tolerates a broad variation in the structure of starting aldehydes as well as
N
-oxides. |
---|---|
ISSN: | 0009-3122 1573-8353 |
DOI: | 10.1007/s10593-019-02431-7 |