Stiffness of liver-mimicking phantom for magnetic resonance elastography

Magnetic Resonance Elastography (MRE) is a powerful technique that presents a graphic scheme of how the properties of different tissues respond when stimulated with mechanical waves [1]. The distortion of the wave suggests an increase in the tissue stiffness. The increase in the stiffness has been i...

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Bibliographic Details
Main Authors: Rojas, Guadalupe Sagaon, Dies, Pilar, Tobón, Silvia Hidalgo
Format: Conference Proceeding
Language:English
Subjects:
Lesions
Liver
Magnetic resonance
Stiffness
Online Access:Get full text
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Summary:Magnetic Resonance Elastography (MRE) is a powerful technique that presents a graphic scheme of how the properties of different tissues respond when stimulated with mechanical waves [1]. The distortion of the wave suggests an increase in the tissue stiffness. The increase in the stiffness has been identified as pathologies [2]. Four phantoms of grenetine gel were produced. The phantoms were created to mimic lesions with varied stiffness. The grenetine concentrations included were 10%, 15% and 20% with the same dimensions. The samples were introduced in a base with a concentration of 5% of grenetine gel. All images were collected at 3.0 T Siemens scanner using the sequence gradient-recalled echo (GRE) based MRE two-dimensional, TR=50 msec, flip angle=25, FoV= 271 mm, slice thickness=5mm. This experiment demonstrated that the technique of Magnetic Resonance Elastography (MRE) shows the map of stiffness in tissue and the way in which mechanical waves propagate in tissue with different densities. The wave pattern shows how the different stiffness destroys gradually the wave.
ISSN:0094-243X
1551-7616
DOI:10.1063/1.5095910