Janus»-like Cu-Fe bimetallic nanoparticles with high antibacterial activity

[Display omitted] •Bimetal Cu/Fe nanoparticles were synthesized by the electrical EEW.•Cu/Fe nanoparticles mostly have «Janus» particle morphology.•Cu/Fe nanoparticles exhibit higher anti-bacterial effect. The search of new efficient antibacterial agents for biomedical applications is subject of res...

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Bibliographic Details
Published in:Materials letters 2019-05, Vol.242, p.187-190
Main Authors: Bakina, O.V., Glazkova, E.A., Svarovskaya, N.V., Rodkevich, N.G., Lerner, M.I.
Format: Article
Language:English
Subjects:
Antibacterial activity
Antibacterial materials
Bimetallic nanoparticles
Bimetals
Biomedical materials
Copper
Drug resistance
Electric explosion of wires
Exploding wires
Iron
Janus»-like nanoparticles
Materials science
Nanoparticles
Silver
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Summary:[Display omitted] •Bimetal Cu/Fe nanoparticles were synthesized by the electrical EEW.•Cu/Fe nanoparticles mostly have «Janus» particle morphology.•Cu/Fe nanoparticles exhibit higher anti-bacterial effect. The search of new efficient antibacterial agents for biomedical applications is subject of researchers special attention. Bimetallic nanoparticles containing biologically active metals are prospective antibacterial agents. The «Janus»-like Cu/Fe nanoparticles prepared by electrical explosive of wires were found to exhibit high antibacterial activity comparable with that of Ag nanoparticles and exceed the antibacterial activity of Fe and Cu monometallic nanoparticles and their mixture. MIC values of bimetallic Cu/Fe particles are 3.91–250 µg/ml. This strong antibacterial activity is due to the synergistic bactericidal Cu2+ and Fe3+ ions released from Cu/Fe bimetallic nanoparticles. Cu/Fe nanoparticles are a promising material for antibacterial protection technologies and for fighting drug-resistant bacterial strains.
ISSN:0167-577X
1873-4979
DOI:10.1016/j.matlet.2019.01.105