TCTAP A-019 Paradoxical Elevation of Cholesterol Efflux Capacity During Acute Coronary Syndrome in Young Heterogenous Asians

[...]assays that quantify apoptotic pathway activation, endothelial vasomotor effects, and antioxidant properties have suggested HDL functional impairment in cardio-metabolic disease states. Most of the young patients in our local data from Sungai Buloh Hospital in Malaysia illustrates that they lac...

Full description

Saved in:
Bibliographic Details
Published in:Journal of the American College of Cardiology 2019-04, Vol.73 (15), p.S9-S10
Main Authors: Chye Chua, Nicholas Yul, Raja Shariff, Raja Ezman, Ismail, Johan Rizwal, Lim, Chiao Wen, Mohd Arshad, Mohd Kamal, Khir, Rizmy Najme, Ibrahim, Khairul Shafiq, Zainal Abidin, Hafisyatul Aiza, Ibrahim, Zubin, Rahman, Effarezan Abdul, Kasim, Sazzli
Format: Article
Language:English
Subjects:
Acute coronary syndromes
Antioxidants
Apoptosis
Cardiology
Cardiovascular disease
Cardiovascular diseases
Cholesterol
Diabetes
Diabetes mellitus
Dyslipidemia
Efflux
Health risk assessment
Health risks
Heart attacks
High density lipoprotein
Hypertension
Lipoproteins
Metabolic disorders
Patients
Risk analysis
Risk factors
Triglycerides
Citations: Items that cite this one
Online Access:Get full text
Tags: Add Tag
No Tags, Be the first to tag this record!
Description
Summary:[...]assays that quantify apoptotic pathway activation, endothelial vasomotor effects, and antioxidant properties have suggested HDL functional impairment in cardio-metabolic disease states. Most of the young patients in our local data from Sungai Buloh Hospital in Malaysia illustrates that they lack the traditional cardiovascular risk factors such as hypertension, diabetes mellitus and dyslipidemia as opposed to their older counterpart. [...]the young acute coronary syndrome patients in our cohort had low high-density lipoprotein, elevated triglycerides, abnormal carotid-intimal medial thickness and paradoxical elevation of cholesterol efflux capacity.
ISSN:0735-1097
1558-3597
DOI:10.1016/j.jacc.2019.03.045