Global scenario of HIV/AIDS: Declining trend and moving toward cure

People living with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) (PLH/PLHA) are increasing worldwide (29.8 million in 2001 and 36.9 million in 2014) mainly owing to the aversion of AIDS related deaths by effective antiretroviral therapy (ART). Although the prevalence is...

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Bibliographic Details
Published in:Indian journal of public health 2016-01, Vol.60 (1), p.59-63
Main Authors: Sekar, Ramalingam, Mythreyee, Manoharan
Format: Article
Language:English
Subjects:
Acquired immune deficiency syndrome
Acquired Immune Deficiency Syndrome (AIDS)-related mortality
Acquired Immunodeficiency Syndrome - drug therapy
Acquired Immunodeficiency Syndrome - epidemiology
AIDS
AIDS (Disease)
Antiretroviral agents
Antiretroviral drugs
Antiretroviral therapy
Aversion
Care and treatment
Disease prevention
Disease transmission
Drug therapy
Fatalities
Health aspects
Highly active antiretroviral therapy
HIV
HIV cure
HIV Infections - drug therapy
HIV Infections - epidemiology
Human immunodeficiency virus
Human Immunodeficiency Virus (HIV)/AIDS
Humans
incidence
India - epidemiology
Infections
Latent infection
Mortality
Prevalence
Public health
Tuberculosis
Viruses
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Summary:People living with Human Immunodeficiency Virus/Acquired Immune Deficiency Syndrome (HIV/AIDS) (PLH/PLHA) are increasing worldwide (29.8 million in 2001 and 36.9 million in 2014) mainly owing to the aversion of AIDS related deaths by effective antiretroviral therapy (ART). Although the prevalence is increasing, the new HIV infections decreased from 3.4 million in 2001 to 2 million in 2014, and AIDS-related deaths were decreased from the peak of 2.4 million in 2005 to 1.2 million in 2014. Implementation of ART with wide coverage and free access, especially in low- and middle-income countries is an important reason for the decline of AIDS-related deaths. Further, it is expected that the recent understanding in the mechanisms of latent infection and importance of reservoir could help to achieve a "functional cure" from HIV infection in near future.
ISSN:0019-557X
2229-7693
DOI:10.4103/0019-557X.177310