Consensus recommendations for managing osteoarthritic pain with topical NSAIDs in Asia-Pacific

Osteoarthritis prevalence is expected to increase markedly in the Asia-Pacific region due to rapid population aging. Identifying effective and safe therapeutic options to manage osteoarthritic pain is viewed as a priority. The Asia-Pacific Experts on Topical Analgesics Advisory Board developed conse...

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Bibliographic Details
Published in:Pain management (London) 2018-03, Vol.8 (2), p.115-128
Main Authors: Rafanan, Bonifacio S, Valdecañas, Benedict F, Lim, Boon Ping, Malairungsakul, Anan, Tassanawipas, Warat, Shiyi, Chen, Tse, Lung Fung, Luong, Tuan Khanh
Format: Article
Language:English
Subjects:
Arthritis
Asia-Pacific
Chinese medicine
Clinical practice guidelines
consensus statements
diclofenac
ketoprofen
Nonsteroidal anti-inflammatory drugs
osteoarthritic pain
Pain management
phonophoresis
skin permeation
topical NSAIDs
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Summary:Osteoarthritis prevalence is expected to increase markedly in the Asia-Pacific region due to rapid population aging. Identifying effective and safe therapeutic options to manage osteoarthritic pain is viewed as a priority. The Asia-Pacific Experts on Topical Analgesics Advisory Board developed consensus statements for use of topical NSAIDs in musculoskeletal pain. Evidence supporting these statements in osteoarthritic pain was reviewed. Best available evidence indicates that topical NSAIDs have a moderate effect on relief of osteoarthritic pain, comparable to that of oral NSAIDs but with a better risk-to-benefit ratio. International clinical practice guidelines recommend topical NSAIDs on par with or ahead of oral NSAIDs for pain management in patients with knee and hand osteoarthritis, and as the first-line choice in persons aged ≥75 years.
ISSN:1758-1869
1758-1877
DOI:10.2217/pmt-2017-0047