Do recombinant human erythropoietin and iron supplementation increase the risk of retinopathy of prematurity?

Comparing a group of infants treated with recombinant erythropoietin and iron supplementation to a group of control infants, no difference was observed concerning the transfusion need. The incidence of retinopathy of prematurity was significantly higher in the treated group. These data need to be co...

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Published in:European journal of pediatrics 2000-08, Vol.159 (8), p.627-628
Main Authors: ROMAGNOLI, C, ZECCA, E, GALLINI, F, GIRLANDO, P, ZUPPA, A. A
Format: Article
Language:English
Subjects:
Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Transfusion
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Erythropoietin - adverse effects
Ferric Compounds - adverse effects
Ferritins - blood
Hematocrit
Humans
Incidence
Infant, Newborn
Intensive care medicine
Medical sciences
Ophthalmology
Recombinant Proteins
Respiratory Distress Syndrome, Newborn - therapy
Retinopathies
Retinopathy of Prematurity - classification
Retinopathy of Prematurity - diagnosis
Retinopathy of Prematurity - etiology
Severity of Illness Index
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cited_by cdi_FETCH-LOGICAL-c339t-6e5ba696e20ed2f0769ed9af9f710332f81af7f3f88ae8aca189b0772f9d6d3d3
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container_end_page 628
container_issue 8
container_start_page 627
container_title European journal of pediatrics
container_volume 159
creator ROMAGNOLI, C
ZECCA, E
GALLINI, F
GIRLANDO, P
ZUPPA, A. A
description Comparing a group of infants treated with recombinant erythropoietin and iron supplementation to a group of control infants, no difference was observed concerning the transfusion need. The incidence of retinopathy of prematurity was significantly higher in the treated group. These data need to be confirmed in randomized controlled studies.
doi_str_mv 10.1007/PL00008390
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subjects Anesthesia. Intensive care medicine. Transfusions. Cell therapy and gene therapy
Biological and medical sciences
Blood Transfusion
Emergency and intensive care: neonates and children. Prematurity. Sudden death
Erythropoietin - adverse effects
Ferric Compounds - adverse effects
Ferritins - blood
Hematocrit
Humans
Incidence
Infant, Newborn
Intensive care medicine
Medical sciences
Ophthalmology
Recombinant Proteins
Respiratory Distress Syndrome, Newborn - therapy
Retinopathies
Retinopathy of Prematurity - classification
Retinopathy of Prematurity - diagnosis
Retinopathy of Prematurity - etiology
Severity of Illness Index
title Do recombinant human erythropoietin and iron supplementation increase the risk of retinopathy of prematurity?
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