Microscopic polyarteritis with renal and cerebral involvement

We report a 15-year-old girl who presented with renal failure requiring dialysis and a diagnosis of p-ANCA-associated vasculitis. She subsequently developed cerebral vasculitis during treatment with oral cyclophosphamide and prednisolone. Treatment with intravenous cyclophosphamide and plasma exchan...

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Bibliographic Details
Published in:Pediatric nephrology (Berlin, West) West), 2000-11, Vol.15 (1-2), p.134-135
Main Authors: Deshpande, P V, Gilbert, R, Alton, H, Milford, D V
Format: Article
Language:English
Subjects:
Acute Kidney Injury - etiology
Acute Kidney Injury - therapy
Adolescent
Antibodies, Antineutrophil Cytoplasmic - blood
Brain - pathology
Cyclophosphamide - adverse effects
Cyclophosphamide - therapeutic use
Female
Glomerulonephritis - etiology
Glomerulonephritis - therapy
Humans
Magnetic Resonance Imaging
Occipital Lobe - pathology
Peritoneal Dialysis
Plasma Exchange
Polyarteritis Nodosa - complications
Polyarteritis Nodosa - diagnosis
Polyarteritis Nodosa - therapy
Prednisolone - adverse effects
Prednisolone - therapeutic use
Vasculitis - diagnosis
Vasculitis - etiology
Vasculitis, Central Nervous System - diagnosis
Vasculitis, Central Nervous System - etiology
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Summary:We report a 15-year-old girl who presented with renal failure requiring dialysis and a diagnosis of p-ANCA-associated vasculitis. She subsequently developed cerebral vasculitis during treatment with oral cyclophosphamide and prednisolone. Treatment with intravenous cyclophosphamide and plasma exchange produced a complete recovery.
ISSN:0931-041X
1432-198X
DOI:10.1007/s004670000428