Molecular Docking Analysis of Bioactive Compounds of Acacia Concinna against Fungal Protein

Methanol extract of the plant bark showed antibacterial activity against gram positive bacteria staphylococcus aureus, Streptococcus mutans, Lactobacillus casei, Lactobacillus acidophilus, and Bacillus megaterium. Materials And Method Bioactive compounds of Gas Chromatography- Mass Spectrometry (GC-...

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Bibliographic Details
Published in:Journal of pharmaceutical sciences and research 2019-04, Vol.11 (4), p.1216-1222
Main Authors: Biswal, Abhishek R, Mirunalini, K, Jayshree, P, Pazhamalai, Vivek
Format: Article
Language:English
Subjects:
Alzheimer's disease
Constipation
Gum disease
Hair
Herbal medicine
Immunology
Infections
Phytochemicals
Proteins
Psoriasis
Quantitative analysis
Skin
Surfactants
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Summary:Methanol extract of the plant bark showed antibacterial activity against gram positive bacteria staphylococcus aureus, Streptococcus mutans, Lactobacillus casei, Lactobacillus acidophilus, and Bacillus megaterium. Materials And Method Bioactive compounds of Gas Chromatography- Mass Spectrometry (GC-MS) analysis from Acacia concinia A. concinia volatile organic compounds extract through distillation process. [...]the binding interactions of amino acid along with bio active compounds are shown in Figure 2-7. The geranyl acetone with binding energy -4.25 Kcal/mol showed better results than the control docking of pepstatin A with binding energy of +1.4 Kcal/mol. [...]the active compounds of Acacia concinna inhibits the virulent enzymes that leads to anti fungal activity with novel discovery of plant based therapeutic product.
ISSN:0975-1459