Erythema nodosum associated with antiphospholipid antibodies: a report of three cases

Erythema nodosum is a dermatologic condition characterized by painful, erythematous nodules on the anterior surfaces of the lower extremities. Its association with a variety of conditions has been previously described. We present three cases of erythema nodosum in patients with elevated anticardioli...

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Bibliographic Details
Published in:Lupus 2000-01, Vol.9 (8), p.641-645
Main Authors: Nekhlyudov, L, Gradzka, M, Conti-Kelly, A M, Greco, T P
Format: Article
Language:English
Subjects:
Adult
Antibodies, Antiphospholipid - blood
Autoantibodies - blood
beta 2-Glycoprotein I
Erythema Nodosum - blood
Erythema Nodosum - diagnosis
Erythema Nodosum - immunology
Female
Follow-Up Studies
Glycoproteins - immunology
Humans
Immunoglobulin A - blood
Immunoglobulin G - blood
Middle Aged
Pregnancy
Pregnancy Complications - blood
Pregnancy Complications - immunology
Recurrence
Skin - pathology
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Summary:Erythema nodosum is a dermatologic condition characterized by painful, erythematous nodules on the anterior surfaces of the lower extremities. Its association with a variety of conditions has been previously described. We present three cases of erythema nodosum in patients with elevated anticardiolipin antibodies. In one patient, a temporal relationship was seen in the simultaneous detection of antibodies and skin lesions. We propose an association between erythema nodosum and the antiphospholipid antibody syndrome (APS).
ISSN:0961-2033
1477-0962
DOI:10.1191/096120300678828767